(S)-4-N-Boc-2-Methyl Piperazine (S)-4-N-叔丁氧羰基-2-甲基哌嗪

CAS 147081-29-6 MFCD02683204

化学结构图

147081-29-6
SMILES: C[C@@H]1CN(CCN1)C(=O)OC(C)(C)C |&1:1|

化学属性

Mol. FormulaC10H20N2O2
Mol. Weight200
TSCANo
Melting Point38-41

别名和识别编码

Chemical Name(S)-4-N-Boc-2-Methyl Piperazine
Synonym tert-Butyl (S)-3-methyl-1-piperazinecarboxylate (S)-3-甲基-1-哌嗪羧酸叔丁酯 (S)-1-Boc-3-甲基哌嗪
MDL NumberMFCD02683204
PubChem Substance ID57651931
CAS Number147081-29-6
Chemical Name Translation(S)-4-N-叔丁氧羰基-2-甲基哌嗪
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SA} Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Heterocyclic Building Blocks, Piperazines
  • Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Heterocyclic Building Blocks, Piperazines

相关文献及参考

  • 1. C. Xue, et al., , Discovery of INCB9471, a Potent, Selective, and Orally Bioavailable CCR5 Antagonist with Potent Anti-HIV-1 Activity ACS Med. Chem. Lett. 1 , 483-487, (2010)
  • 2. J. R. Tagat, et al., , Piperazine-based CCR5 antagonists as HIV-1 inhibitors. I: 2(S)-methyl piperazine as a key pharmacophore element Bioorg. Med. Chem. Lett. 11 , 2143-2146, (2001)
  • 3. F. I. Carroll, et al., , 1-Substituted 4-(3-Hydroxyphenyl)piperazines Are Pure Opioid Receptor Antagonists ACS Med. Chem. Lett. 1 , 365-369, (2010)
  • 4. M. Yu, et al., , Identification of piperazine-bisamide GHSR antagonists for the treatment of obesity Bioorg. Med. Chem. Lett. 20 , 1758-1762, (2010)
  • 5. E. Elzein, et al., , CVT-4325: a potent fatty acid oxidation inhibitor with favorable oral bioavailability Bioorg. Med. Chem. Lett. 14 , 6017-6021, (2004)

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P330+P331
  • P305+P351+P338
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
Signal word Danger
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H318 Causes serious eye damage 严重伤害眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes 8
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S37 Wear suitable gloves 戴适当手套;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Risk Statements
  • R34 Causes burns 会导致灼伤
Storage condition Air Sensitive
UN Number 3259
Packing GroupIII

系列性分类


相关产品推荐