Boronic acid, B-​(2-​chloro-​3-​pyridinyl)​- 2-氯吡啶-3-硼酸

CAS 381248-04-0 MFCD03094997

化学结构图

381248-04-0
SMILES: OB(O)C1C=CC=NC=1Cl

化学属性

Mol. FormulaC5
Mol. Weight157
Melting Point151-153
TSCANo
Density1.41

别名和识别编码

Chemical NameBoronic acid, B-​(2-​chloro-​3-​pyridinyl)​-
CAS Number381248-04-0
Alfabeta NameCHLOROPYRIDINEBORONICACID 23---
MDL NumberMFCD03094997
Synonym 2-氯吡啶-3-硼酸 (2-Chloropyridin-3-yl)boronic acid (2-Chloro-3-pyridyl)boronic acid Dihydroxy(2-chloro-3-pyridyl)borane (2-Chloro-3-pyridyl)boronic acid (2-Chloropyridin-3-yl)boronic acid Dihydroxy(2-chloro-3-pyridyl)borane
Reaxys-RN9119913
EC Number000-000-0
Beilstein Registry Number9119913
Chemical Name Translation2-氯吡啶-3-硼酸
PubChem Substance ID135727096
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分类

  • {SNA} Boronic Acids, Boronic Acids and Derivatives, Chemical Synthesis, Heteroaryl Boronic Acids, Organometallic Reagents

相关文献及参考

  • 1. Ioannidou, H. A.; et al., Three-Step Synthesis of Ethyl Canthinone-3-carboxylates from Ethyl 4-Bromo-6-methoxy-1,5-naphthyridine-3-carboxylate via a Pd-Catalyzed Suzuki-Miyaura Coupling and a Cu-Catalyzed Amidation Reaction J. Org. Chem. 76 , 5113-5122, (2011)
  • 2. Grob, J. E.; et al., One-pot reductive amination and Suzuki-Miyaura cross-coupling of formyl aryl and heteroaryl MIDA boronates in array format J. Org. Chem. 76 , 4930-4940, (2011)
  • 3. Crombie, A. L.; et al., Synthesis and evaluation of azabicyclo[3.2.1]octane derivatives as potent mixed vasopressin antagonists Bioorg. Med. Chem. Lett. 20 , 3742-3745, (2010)
  • 4. Voisin-Chiret, A. S.; et al., A general synthesis of halo-oligopyridines. The Garlanding concept Tetrahedron 65 , 607-612, (2009)

安全信息

Warnings IRRITANT
GHS Symbol
WGK Germany3
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P332+P313
  • P304+P340
  • P301+P312
  • P302+P352
  • P305+P351+P338+P337+P313
Signal word
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S37 Wear suitable gloves 戴适当手套;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Hazard Codes
UN Number
Packing GroupIII

系列性分类


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