4-Fluoro-2-methoxyphenylboronic acid 4-氟-2-甲氧基苯硼酸

CAS 179899-07-1 MFCD03788423

化学结构图

179899-07-1
SMILES: COC1=CC(F)=CC=C1B(O)O

化学属性

Mol. FormulaC7H8BFO3
Mol. Weight170
Melting Point131-136
TSCANo

别名和识别编码

Chemical Name4-Fluoro-2-methoxyphenylboronic acid
CAS Number179899-07-1
Alfabeta NameFLUOROMETHOXYPHENYLBORONICACID 42---
MDL NumberMFCD03788423
Synonym 4-Fluoro-2-methoxybenzeneboronic acid 4-Fluoro-2-methoxyphenylboronic acid 4-​Fluoro-​2-​methoxybenzeneboronic acid
PubChem Substance ID354334241
Chemical Name Translation4-氟-2-甲氧基苯硼酸
Reaxys-RN9191787
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分类

  • Aryl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Chemical Synthesis, Disubstituted Aryl Boronic Acids, Organometallic Reagents
  • {SA} Aryl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Chemical Synthesis, Disubstituted Aryl Boronic Acids, Organometallic Reagents

相关文献及参考

  • 1. T. Noel and A. J. Musacchio, , Suzuki-Miyaura Cross-Coupling of Heteroaryl Halides and Arylboronic Acids in Continuous Flow Org. Lett. 13 , 5180-5183, (2011) 摘要
  • 2. M. Bondoux, et al., , Palladium-catalyzed C-C coupling: efficient preparation of new 5-thio-ß-D-xylopyranosides as oral venous antithrombotic drugs Tetrahedron Lett. 50 , 3872-3876, (2009)
  • 3. G. Gentile, et al., , Identification of 2-(4-pyridyl)thienopyridinones as GSK-3ß inhibitors Bioorg. Med. Chem. Lett. 21 , 4823-4827, (2011)
  • 4. D. G. Brown, et al., , 2,6-Disubstituted pyrazines and related analogs as NR2B site antagonists of the NMDA receptor with anti-depressant activity Bioorg. Med. Chem. Lett. 21 , 3399-3403, (2011)
  • 5. I. R. Greig, et al., , Discovery of biphenylketones as dual modulators of inflammation and bone loss Bioorg. Med. Chem. Lett. 20 , 5548-5551, (2010)
  • 6. J. J. Letourneau, et al., , Identification and hit-to-lead optimization of a novel class of CB1 antagonists Bioorg. Med. Chem. Lett. 20 , 5499-5453, (2010)

安全信息

Warnings IRRITANT
WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S37 Wear suitable gloves 戴适当手套;
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
GHS Symbol
Signal word Warning
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352+P332+P313+P362+P364
  • P304+P340
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P405 Store locked up. 上锁保管。
  • P501a
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤

系列性分类


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