Boronic acid, B-​(3-​chloro-​4-​methylphenyl)​- 3-氯-4-甲基苯硼酸

CAS 175883-63-3 MFCD04039010

化学结构图

175883-63-3
SMILES: CC1=CC=C(C=C1Cl)B(O)O

化学属性

Mol. FormulaC7H8BClO2
Mol. Weight170
Melting Point228-232
TSCANo
Density1.26

别名和识别编码

Chemical NameBoronic acid, B-​(3-​chloro-​4-​methylphenyl)​-
CAS Number175883-63-3
Alfabeta NameCHLOROMETHYLPHENYLBORONICACID 34---
MDL NumberMFCD04039010
PubChem Substance ID135727132
Reaxys-RN3246539
Synonym 3-Chloro-4-methylphenylboronic acid 3-Chloro-4-methylphenylboronic acid3-Chloro-p-tolylboronic acid 3-氯-4-甲基苯硼酸
EC Number250-023-7
Beilstein Registry Number2384789
Chemical Name Translation3-氯-4-甲基苯硼酸
LabNetwork Molecule IDLN00138874
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分类

  • Aryl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Chemical Synthesis, Disubstituted Aryl Boronic Acids, Organometallic Reagents
  • {SA} Aryl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Chemical Synthesis, Disubstituted Aryl Boronic Acids, Organometallic Reagents

相关文献及参考

  • 1. J. Kim, et al., , Intramolecular Aromatic Carbenoid Insertion of Biaryldiazoacetates for the Regioselective Synthesis of Fluorenes Chem. Asian J. 6 , 2040-2047, (2011)
  • 2. B. Buczik, et al., , 2' Biaryl amides as novel and subtype selective M1 agonists. Part I: Identification, synthesis, and initial SAR Bioorg. Med. Chem. Lett. 20 , 3540-3544, (2010)
  • 3. S. J. Baker, et al., , Identification of a novel boron-containing antibacterial agent (AN0128) with anti-inflammatory activity, for the potential treatment of cutaneous diseases Bioorg. Med. Chem. Lett. 16 , 5963-5967, (2006)
  • 4. A. J. Culshaw, et al., , Identification and Biological Characterization of 6-Aryl-7-isopropylquinazolinones as Novel TRPV1 Antagonists that Are Effective in Models of Chronic Pain J. Med. Chem. 49 , 471-474, (2006)

安全信息

Warnings IRRITANT
WGK Germany3
Signal word Warning
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312
  • P302+P350
  • P302+P352
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
GHS Symbol

系列性分类


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