安全信息
WGK Germany | 2 |
Precautionary statements | |
- P301+P310
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- P301+P312+P330
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Hazard statements | |
- H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
- H413 Maycauselonglastingharmfuleffectstoaquaticlife 可能对水生生物造成长期持续有害影响。
- H318 Causes serious eye damage 严重伤害眼睛
- H301 Toxic if swallowed 吞食有毒
- H302 Harmful if swallowed 吞食有害
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RTECS | SK4920000 |
Signal word |
Danger
Warning |
Safety Statements | |
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
- S39 Wear eye/face protection 戴眼睛/面孔保护装置;
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
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Hazard Codes |
Xn |
Personal Protective Equipment |
dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
Risk Statements | |
- R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
- R22 Harmful if swallowed 吞咽有害
- R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
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TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 60 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal.
(China International Book Trading Corp., POB 2820, Beijing, Peop. Rep.
China) V.1- 1953- Suspended 1966-78. Volume(issue)/page/year:
15,630,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1368 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal.
(China International Book Trading Corp., POB 2820, Beijing, Peop. Rep.
China) V.1- 1953- Suspended 1966-78. Volume(issue)/page/year:
15,630,1980
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 80 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal.
(China International Book Trading Corp., POB 2820, Beijing, Peop. Rep.
China) V.1- 1953- Suspended 1966-78. Volume(issue)/page/year:
15,630,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 251 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal.
(China In
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 100 ug/plate
REFERENCE :
CYLPDN Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal
of Pharmacology. (China International Book Trading Corp., POB 2820,
Beijing, Peop. Rep. China) V.1- 1980- Volume(issue)/page/year:
3,51,1982
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 2320 mg/kg
SEX/DURATION : male 9 week(s) pre-mating
female 2 week(s) pre-mating - 3 week(s) post-birth
TOXIC EFFECTS :
Reproductive - Fertility - post-implantati
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 1100 mg/kg
SEX/DURATION : female 7 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
Reproductive - Specific Developmental Abnormalities - Central Nervous System
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal.
(China International Book Trading Corp., POB 2820, Beijing, Peop. Rep.
China) V.1- 1953- Suspended 1966-78. Volume(issue)/page/year:
17,401,1982
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 252 mg/kg
SEX/DURATION : female 7-9 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
REFERENCE :
YHTPAD Yaoxue Tongbao. Bulletin of Pharmacology. (China International Book
Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.13-23, 1978-88. For
publisher information, see ZYZAEU. Volume(issue)/page/year: 16(11),53,1981
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE