1-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)piperazine hydrochloride 1-(2,3-二氢苯并[b][1,4]二噁英-5-基)哌嗪盐酸盐
CAS 98206-09-8 MFCD06245586
化学结构图
SMILES: Cl.C1COC2C=CC=C(C=2O1)N1CCNCC1
化学属性
| Mol. Formula | C12H17ClN2O2 |
|---|---|
| Mol. Weight | 256.73 |
别名和识别编码
| Chemical Name | 1-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)piperazine hydrochloride |
|---|---|
| CAS Number | 98224-03-4 |
| Synonym | 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)piperazine Hydrochloride DU 28853 DU 28893 |
| Alfabeta Name | DIHYDROBENZODIOXINYLPIPERAZINEHYDROCHLORIDE 123145()------,, |
| MDL Number | MFCD06245586 |
| Chemical Name Translation | 1-(2,3-二氢苯并[b][1,4]二噁英-5-基)哌嗪盐酸盐 |
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分类
- Agonist
- Aromatics
- Heterocycles
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
- 5-HT1 and 5-HT2C receptor partial agonist that has been shown to reduce 5-HIAA levels in the striatum and exhibits antiaggressive behavior in vivo. A novel drug for the treatment of anxiety as well as
相关文献及参考
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- [3]. Bezard E, et al. Study of the antidyskinetic effect of eltoprazine in animal models of levodopa-induced dyskinesia. Mov Disord. 2013 Jul;28(8):1088-96.
- [4]. Rocha B, et al. Chronic mianserin or eltoprazine treatment in rats: effects on the elevated plus-maze test and on limbic 5-HT2C receptor levels. Eur J Pharmacol. 1994 Sep 1;262(1-2):125-31.
- Miczek et al.: Psychopharmacol.Bull., 25, 399 (1989); Schipper et al.: Drug Metabol.Drug Interact., 8, 85 (1990);
- [1]. Sijbesma H, et al. Eltoprazine, a drug which reduces aggressive behaviour, binds selectively to 5-HT1 receptor sites i
- [1]. Sijbesma H, et al. Eltoprazine, a drug which reduces aggressive behaviour, binds selectively to 5-HT1 receptor sites in the rat brain: an autoradiographic study. Eur J Pharmacol. 1990 Feb 20;177(1-2):55-66.
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