3,4-Dihydro-7-Hydroxy-2(1H)-Quinolinone 3,4-二氢-7-羟基-2(1H)-喹啉酮

CAS 22246-18-0 MFCD06410891

化学结构图

22246-18-0
SMILES: O=C1CCc2ccc(O)cc2N1

化学属性

Mol. FormulaC9H9NO2
Mol. Weight163
Melting Point233.0 to 239.0 deg-C
TSCANo
Density1.282

别名和识别编码

Chemical Name3,4-Dihydro-7-Hydroxy-2(1H)-Quinolinone
CAS Number22246-18-0
Alfabeta NameHYDROXYDIHYDROCARBOSTYRIL 734---,
MDL NumberMFCD06410891
Synonym 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone, 7-Hydroxy-1,2,3,4-tetrahydro-2-quinolinone, 7-Hydroxy-3,4-dihydrocarbostyril 7-Hydroxy-3,4-dihydrocarbostyril 7-Hydroxy-1,2,3,4-tetrahydro-2-chinolinon 7-Hydroxy-3,4-dihydro-2(1H)-chinolinon 7-羟基-2(1H)-3,4-二氢喹啉酮 7-羟基-3,4-二氢喹诺酮 7-羟基-3,4-二氢喹诺酮 7-Hydroxy-3,4-dihydro-2(1H)-chinolinon 7-羟基-2(1H)-3,4-二氢喹啉酮 7-Hydroxy-1,2,3,4-tetrahydro-2-chinolinon 7-Hydroxycarbostyril 7-羟基-3,4-二氢-2(1H)-喹啉酮 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone, 7-​Hydroxy-​1,2,3,4-​tetrahydro-​2-​quinolinone, 7-​Hydroxy-​3,4-​dihydrocarbostyril 4-二氢喹诺酮 7-Hydroxy-1,2,3,4-tetrahydro-2-quinolinone 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone 7-羟基-3 3,4-Dihydro-7-hydroxy-carbostyril
PubChem Substance ID87559946
Reaxys-RN137093
Beilstein Registry Number21(3/4)6085
Chemical Name Translation3,4-二氢-7-羟基-2(1H)-喹啉酮
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分类

  • Building Blocks, C8 to C10, Chemical Synthesis, Heterocyclic Building Blocks, Quinolines

产品应用

  • An antitumor agent. Hydroxyindole analog inhibitor tyrosinase melanoma.

相关文献及参考

  • Beilstein:21(3/4)6085
  • Bouchard, B., et al.: J. Exp. Med., 169, 2029 (1989),
  • Cho, S., et al.: Bioorg. Med. Chem. Lett., 16, 2682 (2006),
  • Kim, Y., et al.: J. Biol. Chem., 277, 16340 (2002),

安全信息

Warnings IRRITANT
WGK Germany3
GHS Symbol
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P332+P313
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P305+P351+P338+P337+P313
  • P301+P312+P330
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P337+P313
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
Signal word
Hazard statements
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H302 Harmful if swallowed 吞食有害
Hazard Codes Xn
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Safety Statements
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S37 Wear suitable gloves 戴适当手套;
Risk Statements
  • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
  • R22 Harmful if swallowed 吞咽有害

系列性分类


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