GW311616A

CAS 197090-44-1 MFCD06411566

化学结构图

197090-44-1
SMILES: Cl.CC(C)[C@H]1[C@H]2[C@@H](CCN2C(=O)/C=C/CN2CCCCC2)N(C1=O)S(C)(=O)=O

化学属性

Mol. FormulaC19H32ClN3O4S
Mol. Weight433.99

别名和识别编码

Chemical NameGW311616A
Synonym (3S,3aS,6aR)-3-Isopropyl-1-(methanesulfonyl)-4-[4-(1-piperidinyl)-2(E)-butenoyl]perhydropyrrolo[3,2b]pyrrol-2(1H)-one hydrochloride
MDL NumberMFCD06411566
CAS Number197090-44-1
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分类

  • Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, D to K, Elastase, neutrophil, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Enzymes, Substrates, Inhibitors &, Modulators for Stem Cell Biology, G, General Stem Cell Biology, GlaxoSmithKline, Inhibitors, Stem Cell Biology, Stem Cell Characterization
  • {SA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, D to K,

相关文献及参考

  • Macdonald, S.J., et al., The discovery of a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase−GW311616A a development candidate. Bioorg. Med. Chem. Lett. 11 , 895-898, (2001)

安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Signal word Warning
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes Xi
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Inhibitors - Enzymes, Inhibitors, and Substrates
  5. Enzyme Inhibitors by Enzyme - Enzyme Inhibitors
  6. D to K - Enzyme Inhibitors by Enzyme
  7. Elastase, neutrophil - D to K

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