Ramelteon 拉梅尔通

CAS 196597-26-9 MFCD08067736

化学结构图

196597-26-9
SMILES: CCC(=O)NCC[C@@H]1CCC2=CC=C3OCCC3=C21

化学属性

Mol. FormulaC16H21NO2
Mol. Weight259.35
Melting Point114.0 to 118.0 deg-C

别名和识别编码

Chemical NameRamelteon
CAS Number196597-26-9
Synonym N-[-[(8S)-1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl]propanamide TAK-375 Rozerem
Chemical Name Translation拉梅尔通
Reaxys-RN9277585
Merck Number8101
MDL NumberMFCD08067736
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Chiral Reagents
  • Pharmaceuticals
  • Intermediates & Fine Chemicals,

产品应用

  • Melatonin MT1/MT2 receptor agonist. Sedative, hypnotic.

相关文献及参考

  • [2]. Miyamoto M, et al. The sleep-promoting action of ramelteon (TAK-375) in freely moving cats. Sleep. 2004 Nov 1;27(7):1319-25.
  • [3]. Kuriyama A, et al. Ramelteon for the treatment of insomnia in adults: a systematic review and meta-analysis. Sleep Med. 2014 Apr;15(4):385-92.
  • [4]. Fisher SP, et al. Acute sleep-promoting action of the melatonin agonist, ramelteon, in the rat. J Pineal Res. 2008 Sep;45(2):125-32.
  • Cajochen, C., et al.: Curr. Opin. Invest. Drugs, 6, 114 (2005),
  • Kato, K., et al.: Neuropharmacology, 48, 301 (2005),
  • Yukuhiro, N., et al.: Brain Res., 59, 1027 (2004),
  • [1]. Kato K, et al. Neurochemical properties of ramelteon (TAK-375), a selective MT1/MT2 receptor agonist. Neuropharmacology. 2005 Feb;48(2):301-10.
  • [1]. Kato K, et al. Neurochemical properties of ramelteon (TAK-375), a selective MT1/MT2 receptor agonist. Neuropharmacology. 2005 Feb;48(2):301-10.
  • [2]. Miyamoto M, et al. The sleep-promoting

安全信息

Hazard statements
  • H302 Harmful if swallowed 吞食有害
RTECSTX1498230
GHS Symbol
Signal word
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312+P330
  • P308+P313
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. Melatonin Receptor  (褪黑素受体)

相关产品推荐