Almotriptan 依来曲普坦

CAS 181183-52-8 MFCD08067740

化学结构图

181183-52-8
SMILES: CN(C)CCC1=CNC2C=CC(CS(=O)(=O)N3CCCC3)=CC=21.OC(=O)CC(O)C(O)=O

化学属性

Mol. FormulaC21H31N3O7S
Mol. Weight469.55

别名和识别编码

Chemical NameAlmotriptan
CAS Number181183-52-8
Synonym 1-[[[2-(Dimethyl-amino)ethyl]-1H-indol-5-yl]methyl]sulfonyl]pyrrolidine Malate 1-[[3-(2-dimethylaminoethyl)-5-indolyl]methanesulphonyl]pyrrolidine Malate LAS-31416 Malate
Chemical Name Translation依来曲普坦
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分类

  • Amines
  • Heterocycles
  • Neurochemicals
  • Pharmaceuticals
  • Intermediates & Fine Chemicals,

产品应用

  • Almotriptan is a serotonin 5HT1B /1D-receptor agonist used for treatment of migraine.

相关文献及参考

  • [2]. Gras J, et al. Safety profile of almotriptan, a new antimigraine agent. Effects on central nervous system, renal function and respiratory dynamics. Arzneimittelforschung, 2001. 51(9): p. 726-32.
  • Fleishaker, J.C., et al.: Clin. Pharmacol. Ther., 67, 498 (2000),
  • Kamali, F., et al.: Curr. Opin. Cent. Peripher. Nerv. Syst. Invest. Drugs, 2, 197 (2000),
  • [1]. Bou J , et al. Pharmacological characterization of almotriptan: an indolic 5-HT receptor agonist for the treatment of migraine. Eur J Pharmacol, 2000. 410(1): p. 33-41.
  • [1]. Bou J , et al. Pharmacological characterization of almotriptan: an indolic 5-HT receptor agonist for the treatment of migraine. Eur J Pharmacol, 2000. 410(1): p. 33-41.
  • [2]. Gras J, et al. Safety profile of almotriptan, a new antimigraine agent. Effects on central nervous system, renal function and respiratory dynamics. Arzneimittelforschung, 2001. 51(9): p. 726-32.

系列性分类


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