ATC0175

CAS 510733-97-8 MFCD08276913

化学结构图

510733-97-8
SMILES: Cl.CN(C)C1=NC(N[C@@H]2CC[C@@H](CC2)NC(=O)C2=CC(F)=C(F)C=C2)=NC2=CC=CC=C21 |&1:8,11|

化学属性

Mol. FormulaC23H26ClF2N5O
Mol. Weight461.94

别名和识别编码

Chemical NameATC0175
Synonym N-(cis-4-{[4-(Dimethylamino)quinazolin-2-yl]amino}cyclohexyl)-3,4-difluorobenzamide HCl
MDL NumberMFCD08276913
PubChem Substance ID24724389
CAS Number510733-97-8
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分类

  • {SNA} AN-AZ, Bioactive Small Molecule Alphabetical Index, Cytokines, Growth Factors and Hormones, Hormones, Obesity Research, Orexin, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
  • {SNA} AN-AZ, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones, Obesity Research, Orexin
  • AN-AZ, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones, Obesity Research, Orexin

相关文献及参考

  • Chaki, S., et al., Anxiolytic- and antidepressant-like profile of ATC0065 and ATC0175: Nonpeptideic and orally active melanin-concentrating hormone receptor 1 antagonists. J. Pharmacol. Exp. Ther. 313 , 831-839, (2005) 摘要

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Signal word Warning
Hazard statements
  • H413 Maycauselonglastingharmfuleffectstoaquaticlife 可能对水生生物造成长期持续有害影响。
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes Xi
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Cytokines, Growth Factors and Hormones - Cell Signaling and Neuroscience
  5. Hormones - Cytokines, Growth Factors and Hormones
  6. Obesity Research - Hormones
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Cytokines, Growth Factors and Hormones - Cell Signaling and Neuroscience
  5. Hormones - Cytokines, Growth Factors and Hormones
  6. Obesity Research - Hormones
  7. Orexin - Obesity Research
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Cytokines, Growth Factors and Hormones - Cell Signaling and Neuroscience
  5. Hormones - Cytokines, Growth Factors and Hormones
  6. Obesity Research - Hormones
  7. Orexin - Obesity Research

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