4-(2,6-di-tert-butyl-4-((2-((3,5-di-tert-butyl-4-hydroxyphenyl)thio)propan-2-yl)thio)phenoxy)-4-oxobutanoic acid 4-(2,6-二叔丁基-4-((2-((3,5-二叔丁基-4-羟基苯基)硫基)丙-2-基)硫基)苯氧基)-4-氧代丁酸

CAS 216167-82-7 MFCD08690469

化学结构图

216167-82-7
SMILES: CC(C)(C)C1C=C(C=C(C=1OC(=O)CCC(O)=O)C(C)(C)C)SC(C)(C)SC1=CC(=C(O)C(=C1)C(C)(C)C)C(C)(C)C

化学属性

Mol. FormulaC35H52O5S2
Mol. Weight616.91

别名和识别编码

Chemical Name4-(2,6-di-tert-butyl-4-((2-((3,5-di-tert-butyl-4-hydroxyphenyl)thio)propan-2-yl)thio)phenoxy)-4-oxobutanoic acid
CAS Number216167-82-7
Synonym Butanedioic Acid 1-[4-[[1-[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-1-methylethyl]thio]-2,6-bis(1,1-dimethylethyl)phenyl] Ester Probucol Monosuccinate
Chemical Name Translation4-(2,6-二叔丁基-4-((2-((3,5-二叔丁基-4-羟基苯基)硫基)丙-2-基)硫基)苯氧基)-4-氧代丁酸
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分类

  • Aromatics
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Sulfur & Selenium Compounds

产品应用

  • An antioxidant and anti-inflammatory.

相关文献及参考

  • [2]. Colle D, et al. Succinobucol, a Lipid-Lowering Drug, Protects Against 3-Nitropropionic Acid-Induced Mitochondrial Dysfunction and Oxidative Stress in SH-SY5Y Cells via Upregulation of Glutathione Levels and Glutamate Cysteine Ligase Activity. Mol Neurobiol. 2016 Mar;53(2):1280-95.
  • [3]. Dan Z, et al. A pH-Responsive Host-guest Nanosystem Loading Succinobucol Suppresses Lung Metastasis of Breast Cancer. Theranostics. 2016 Jan 25;6(3):435-45.
  • Cyprus, T., et al.: Devel. Cardiovas. Med., 258, 227 (2006),
  • Stocker, R., et al.: Curr. Opinion Lipidol., 20, 227 (2009),
  • Wu, B., et al.: Arteriosclero., Thrombo., Vasc. Biol., 29, 1537 (2009),
  • [1]. Houston SA, et al. An investigation of the antiplatelet effects of succinobucol (AGI-1067). Platelets. 2017 May;28(3):295-300.
  • [1]. Houston SA, et al. An investigation of the antiplatelet effects of succinobucol (AGI-1067). Platelets. 2017 May;28(3):295-300.
  • [2]. Colle D, et al. Succino

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Reactive Oxygen Species  (活性氧)

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