Voacamine

CAS 3371-85-5 MFCD09837906

化学结构图

3371-85-5
SMILES: C/C=C1/CN(C)[C@H]2Cc3c([nH]c4ccccc34)[C@H](c3cc4[nH]c5c(c4cc3OC)CCN3C[C@@H]4C[C@H](CC)[C@H]3[C@@]5(C(=O)OC)C4)C[C@@H]1[C@@H]2C(=O)OC

化学属性

Mol. FormulaC43H52N4O5
Mol. Weight704.907

别名和识别编码

Chemical NameVoacamine
PubChem Substance ID11953931
InChIInChI=1S/C43H52N4O5/c1-7-24-15-23-20-43(42(49)52-6)39-27(13-14-47(21-23)40(24)43)29-19-36(50-4)30(17-34(29)45-39)31-16-28-25(8-2)22-46(3)35(37(28)41(48)51-5)18-32-26-11-9-10-12-33(26)44-38(31)32/h8-12,17,19,23-24,28,31,35,37,40,44-45H,7,13-16,18,20-22H2,1-6H3/b25-8-/t23-,24-,28-,31+,35+,37?,40-,43+/m0/s1
LabNetwork Molecule IDLN04696233
Synonym voacamine
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相关文献及参考

  • [2]. Meschini S, et al. Voacamine, an alkaloid extracted from Peschiera fuchsiaefolia , inhibits P-glycoprotein action in multidrug-resistant tumor cells. Int J Oncol. 2005 Dec;27(6):1597-603.
  • [1]. Kitajima M, et al. Discovery of indole alkaloids with cannabinoid CB1 receptor antagonistic activity. Bioorg Med Chem Lett. 2011 Apr 1;21(7):1962-4.
  • [1]. Kitajima M, et al. Discovery of indole alkaloids with cannabinoid CB1 receptor antagonistic activity. Bioorg Med Chem Lett. 2011 Apr 1;21(7):1962-4.
  • [2]. Meschini S, et al. Voacamine, an alkaloid extracted from Peschiera fuchsiaefolia , inhibits P-glycoprotein action in multidrug-resistant tumor cells. Int J Oncol. 2005 Dec;27(6):1597-603.

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. Cannabinoid Receptor  (大麻素受体)

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