Asenapine
CAS 65576-45-6 MFCD09838016
化学结构图
SMILES: CN1C[C@@H]2[C@@H](C1)C1C=C(Cl)C=CC=1OC1C=CC=CC=12 |&1:3,4|
化学属性
| Mol. Formula | C17H16ClNO |
|---|---|
| Mol. Weight | 285.77 |
别名和识别编码
| Chemical Name | Asenapine |
|---|---|
| CAS Number | 65576-45-6 |
| Synonym | (3aR,12bR)-rel-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole trans-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7] |
| Chemical Name Translation |
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分类
- Aromatics
- Heterocycles
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
- Combined serotonin (5HT2) and dopamine (D2) receptor antagonist; structurally related to Mianserin. Antipsychotic.
相关文献及参考
- [2]. Olivia Frånberg, et al. Asenapine, a novel psychopharmacologic agent: preclinical evidence for clinical effects in schizophrenia. Psychopharmacology (Berl). 2008 Feb;196(3):417-29.
- Meltzer, H., et al.: J. Pharmacol. Exp. Ther., 251, 238 (1989),
- [1]. M Shahid, et al. Asenapine: a novel psychopharmacologic agent with a unique human receptor signature. J Psychopharmacol. 2009 Jan;23(1):65-73.
- [1]. M Shahid, et al. Asenapine: a novel psychopharmacologic agent with a unique human receptor signature. J Psychopharmacol. 2009 Jan;23(1):65-73.
- [2]. Olivia Frånberg, et al. Asenapine, a novel psychopharmacologic agent: preclinical evidence for clinical effects in schizophrenia. Psychopharmacology (Berl). 2008 Feb;196(3):417-29.
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