Solifenacin Hydrochloride
CAS 180468-39-7 MFCD09953430
化学结构图
SMILES: Cl.O=C(O[C@H]1CN2CCC1CC2)N1CCC2C=CC=CC=2[C@@H]1C1C=CC=CC=1
化学属性
| Mol. Formula | C23H27ClN2O2 |
|---|---|
| Mol. Weight | 398.93 |
别名和识别编码
| Chemical Name | Solifenacin Hydrochloride |
|---|---|
| CAS Number | 180468-39-7 |
| Synonym | (1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid (3R)-1-Azabicyclo-[2.2.2]oct-3-yl Ester Hydrochloride |
| Chemical Name Translation |
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分类
- Amines
- Aromatics
- Chiral Reagents
- Heterocycles
- Pharmaceuticals
- Intermediates & Fine Chemicals,
产品应用
- Muscarinic M3 receptor antagoinst. Used in treatment of urinary incontinence.
相关文献及参考
- [2]. Krishna SR, Rao BM, Rao NS.A validated rapid stability-indicating method for the determination of related substances in solifenacin succinate by ultra-fast liquid chromatography.J Chromatogr Sci. 2010 Nov;48(10):807-10.
- [3]. Ohtake A, Sato S, Sasamata M, Miyata K.The forefront for novel therapeutic agents based on the pathophysiology of lower urinary tract dysfunction: ameliorative effect of solifenacin succinate (Vesicare), a bladder-selective antimuscarinic agent, on overactive bladder symptoms, especially urgency episodes.J Pharmacol Sci. 2010;112(2):135-41. Epub 2010 Feb 4.
- [4]. Hoffstetter S, Leong FC.Solifenacin succinate for the treatment of overactive bladder.Expert Opin Drug Metab Toxicol. 2009 Mar;5(3):345-50.
- [5]. Choo MS, Lee JZ, Lee JB, Kim YH, Jung HC, Lee KS, Kim JC, Seo JT, Paick JS, Kim HJ, Na YG, Lee JG.Efficacy and safety of solifenacin succinate in Korean patients with overactive bladder: a randomised, prospective, double-b
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