(1R,3R,4S,5R)-1,3-Bis((3-(3,4-Dihydroxyphenyl)Acryloyl)Oxy)-4,5-Dihydroxycyclohexanecarboxylic Acid (1R,3R,4S,5R)-1,3-双((3-(3,4-二羟基苯基)丙烯酰基)氧基)-4,5-二羟基环己烷甲酸

CAS 30964-13-7 MFCD00075714

化学结构图

30964-13-7
SMILES: OC(=O)[C@@]1(C[C@H](O)[C@@H](OC(=O)/C=C/C2C=C(O)C(O)=CC=2)[C@@H](O)C1)OC(=O)/C=C/C1C=C(O)C(O)=CC=1 |&1:3,5,7,21|

化学属性

Mol. FormulaC25H24O12
Mol. Weight516.46
Melting Point225-227 ºC
Density1.64

别名和识别编码

Chemical Name(1R,3R,4S,5R)-1,3-Bis((3-(3,4-Dihydroxyphenyl)Acryloyl)Oxy)-4,5-Dihydroxycyclohexanecarboxylic Acid
EC Number214-655-7
Synonym 菜蓟素 1,4-Dicaffeylquinic acid; 1,4-Bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-3,5-dihydroxycyclohexane-1-carboxylic acid 朝蓟素 洋蓟素 1,3-二咖啡酰奎尼酸
CAS Number1182-34-9
Chemical Name Translation(1R,3R,4S,5R)-1,3-双((3-(3,4-二羟基苯基)丙烯酰基)氧基)-4,5-二羟基环己烷甲酸
InChIKeyIYXQRCXQQWUFQV-PSEXTPKNSA-N
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产品应用

  • 洋蓟素(1,3-二咖啡酰奎宁酸),又称朝蓟素,洋蓟酸。存在于菊科植物洋蓟(Cynara scolymus L. )、森林千里光(Senecio nemorensis L. )全草中,也可化学合成。具有利胆、保肝、降胆固醇作用。临床用于治疗由肝功能不足引起的各种疾病。还可作为利胆药。

相关文献及参考

  • [2]. Dong GC, et al. Blocking effect of an immuno-suppressive agent, cynarin, on CD28 of T-cell receptor. Pharm Res. 2009 Feb;26(2):375-81.
  • [1]. Topal M, et al. Antioxidant, antiradical, and anticholinergic properties of cynarin purified from the Illyrian thistle (Onopordum illyricum L.). J Enzyme Inhib Med Chem. 2016;31(2):266-75.
  • [1]. Topal M, et al. Antioxidant, antiradical, and anticholinergic properties of cynarin purified from the Illyrian thistle (Onopordum illyricum L.). J Enzyme Inhib Med Chem. 2016;31(2):266-75.
  • [2]. Dong GC, et al. Blocking effect of an immuno-suppressive agent, cynarin, on CD28 of T-cell receptor. Pharm Res. 2009 Feb;26(2):375-81.

安全信息

Storage condition 低温储存2-8°C
GHS Symbol
Safety Statements
Precautionary statements

系列性分类


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