Glp-Asn-Pro-d-Tyr-d-Trp-NH2

CAS 882400-49-9 MFCD11114385

化学结构图

882400-49-9
SMILES: NC(=O)C[C@H](NC(=O)[C@@H]1CCC(=O)N1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CC1C=CC(O)=CC=1)C(=O)N[C@H](CC1=CNC2C=CC=CC1=2)C(N)=O

化学属性

Mol. FormulaC34H40N8O8
Mol. Weight688.73

别名和识别编码

Chemical NameGlp-Asn-Pro-d-Tyr-d-Trp-NH2
Synonym Glp-Asn-Pro-d-Tyr-d-Trp-NH2 JAK4D
MDL NumberMFCD11114385
CAS Number882400-49-9
PubChem Substance ID329799939
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分类

  • Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, G, Hormones, Pituitary Hormones, Thyrotropic Hormone
  • {SNA} Cytokines, Growth Factors and Hormones, Hormones, Pituitary Hormones, Thyrotropic Hormone, 细胞信号转导和神经科学,

相关文献及参考

  • Hogan N., et al., A novel TRH analog, Glp-Asn-Pro-D-Tyr-D-TrpNH2, binds to [3H][3-Me-His2]TRH-labelled sites in rat hippocampus and cortex but not pituitary or heterologous cells expressing TRHR1 or TRHR2. Neurosci. Lett. 431 , 26-30, (2008)
  • Kelly J.A., et al., Kinetic investigation of the specificity of porcine brain thyrotropin-releasing hormone-degrading ectoenzyme for thyrotropin-releasing hormone-like peptides. J. Biol. Chem. 275 , 16746-51, (2000) 摘要
  • Scalabrino G.A., et al., Discovery of a dual action first-in-class peptide that mimics and enhances CNS-mediated actions of thyrotropin-releasing hormone. Neuropharmacology 52 , 1472-81, (2007) 摘要

安全信息

WGK Germany2
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类


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