4-(4-Pyrazolyl)-7-[[2-(Trimethylsilyl)Ethoxy]Methyl]-7H-Pyrrolo[2,3-D]Pyrimidine 4-(4-吡唑基)-7-[[2-(三甲基硅基)乙氧基]甲基]-7H-吡咯并[2,3-d]嘧啶
CAS 941685-27-4 MFCD11857754
化学结构图
SMILES: C[Si](C)(C)CCOCN1C=CC2C1=NC=NC=2C1C=NNC=1
化学属性
| Mol. Formula | C15H21N5OSi |
|---|---|
| Mol. Weight | 315.45 |
别名和识别编码
| Chemical Name | 4-(4-Pyrazolyl)-7-[[2-(Trimethylsilyl)Ethoxy]Methyl]-7H-Pyrrolo[2,3-D]Pyrimidine |
|---|---|
| Alfabeta Name | PYRAZOLYLTRIMETHYLSILYLETHOXYMETHYLPYRROLOPYRIMIDINE HHD41472723[](((())))-----------, |
| MDL Number | MFCD11857754 |
| CAS Number | 941685-27-4 |
| Synonym | 4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine INCB032304 |
| PubChem Substance ID | 329772298 |
| Chemical Name Translation | 4-(4-吡唑基)-7-[[2-(三甲基硅基)乙氧基]甲基]-7H-吡咯并[2,3-d]嘧啶 |
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分类
- {SNA} Building Blocks, C10-C30+, C12 to C30+, C12 to C37, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, Organometallic Reagents, Organosilicon, Other Organosilicon, Pyrazoles, Pyrimidines
- Heterocycles
- Pharmaceuticals
- Intermediates & Fine Chemicals
- {SNA} Building Blocks
产品应用
- 4-(1H-Pyrazol-4-yl)-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine is an important intermediate in the preparation of the janus kinase inhibitor INCB018424.
相关文献及参考
- Lin, Q. et al.: Org. Lett., 11, 1999 (2009);
安全信息
GHS Symbol
- H302 Harmful if swallowed 吞食有害
- R22 Harmful if swallowed 吞咽有害
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