LY-404039 (1r,4s,5s,6s)-4-氨基-2-硫杂双环[3.1.0]己烷-4,6-二甲酸2,2-二氧化物

CAS 635318-11-5 MFCD11974011

化学结构图

635318-11-5
SMILES: N[C@]1(CS(=O)(=O)[C@H]2[C@@H]([C@@H]12)C(O)=O)C(O)=O

化学属性

Mol. FormulaC7H9NO6S
Mol. Weight235.215

别名和识别编码

Chemical NameLY-404039
Chemical Name Translation(1r,4s,5s,6s)-4-氨基-2-硫杂双环[3.1.0]己烷-4,6-二甲酸2,2-二氧化物
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相关文献及参考

  • [2]. Seeman P. An agonist at glutamate and dopamine D2 receptors, LY404039. Neuropharmacology. 2013 Mar;66:87-8.
  • [3]. Rorick-Kehn LM, et al. In vivo pharmacological characterization of the structurally novel, potent, selective mGlu2/3 receptor agonistLY404039 in animal models of psychiatric disorders. Psychopharmacology (Berl). 2007 Jul;193(1):121-36.
  • [1]. Linda M Rorick-Kehn, et al. Pharmacological and pharmacokinetic properties of a structurally novel, potent, and selective metabotropic glutamate 2/3 receptor agonist: in vitro characterization of agonist (-)-(1R,4S,5S,6S)-4-amino-2-sulfonylbicyclo[3.1.0]-hexan
  • [1]. Linda M Rorick-Kehn, et al. Pharmacological and pharmacokinetic properties of a structurally novel, potent, and selective metabotropic glutamate 2/3 receptor agonist: in vitro characterization of agonist (-)-(1R,4S,5S,6S)-4-amino-2-sulfonylbicyclo[3.1.0]-hexane-4,6-dicarboxylic acid (LY404039). J Pharmacol Exp Ther. 2007 Apr;321(1):308-17.

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. mGluR  (代谢型谷氨酸受体)

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