2,4-Dichloro-5,6,7,8-tetrahydroquinazoline 2,4-二氯-5,6,7,8-四氢喹唑啉

CAS 1127-85-1 MFCD09750204

化学结构图

1127-85-1
SMILES: Clc1nc(Cl)c2c(n1)CCCC2

化学属性

Mol. FormulaC8H8Cl2N2
Mol. Weight203.07
Melting Point72-73 °C
Boiling Point325.6±42.0 °C at 760 mmHg

别名和识别编码

Chemical Name2,4-Dichloro-5,6,7,8-tetrahydroquinazoline
CAS Number1127-85-1
Alfabeta NameDICHLOROCYCLOPENTAPYRIMIDINE HHHD24567[]---,,,
MDL NumberMFCD12400774
Synonym 2,4-Dichloro-5,6,7,8-tetrahydroquinazoline {LY} 2,4-Dichloro-5,6,7,8-tetrahydroquinazoline {} {LY} 2,4-Dichloro-5,6,7,8-tetrahydroquinazoline {} {} {LY} 2,4-Dichloro-5,6,7,8-tetrahydroquinazoline {} {} {} {LY} 2,4-Dichloro-5,6,7,8-tetrahydroquinazoline {} {} {} {} {LY} 2,4-Dichloro-5,6,7,8-tetrahydroquinazoline {} {} {} {} {} {LY} 2,4-Dichloro-5,6,7,8-tetrahydroquinazoline {} {} {} {} {} {} {LY} 2,4-Dichloro-5,6,7,8-tetrahydroquinazoline {} {} {} {} {} {} {} {LY} 2,4-Dichloro-5,6,7,8-tetrahydroquinazoline {} {} {} {} {} {} {} {} {LY} 2,4-Dichloro-5,6,7,8-tetrahydroquinazoline {} {} {} {} {} {} {} {} {} {LY} 2,4-Dichloro-5,6,7,8-tetrahydroquinazoline {} {} {} {} {} {} {} {} {} {} {LY} 2,4-Dichloro-5,6,7,8-tetrahydroquinazoline {} {} {} {} {} {} {} {} {} {} {} {LY} 2,4-Dichloro-5,6,7,8-tetrahydroquinazoline {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2,4-Dichloro-5,6,7,8-tetrahydroquinazoline {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2,4-Dichloro-5,6,7,8-tetrahydroqui
Chemical Name Translation2,4-二氯-5,6,7,8-四氢喹唑啉
PubChem Substance ID12602864
InChIInChI=1S/C8H8Cl2N2/c9-7-5-3-1-2-4-6(5)11-8(10)12-7/h1-4H2
Canonical SMILESClC1=C2CCCCC2=NC(Cl)=N1
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分类

  • {KO} ReacChlorides
  • {SNA} Building Blocks, C6 to C8, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, New Products for Chemical Synthesis, Pyrimidines

安全信息

Warnings IRRITANT
Hazard Codes Xn
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
GHS Symbol
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P317
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P332+P317
  • P337+P317
  • P362+P364
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Signal word Warning
Risk Statements
  • R36 Irritating to eyes 刺激眼睛
  • R22 Harmful if swallowed 吞咽有害
Storage condition -20°C, sealed storage, away from moisture {LY} -20°C, sealed storage, away from moisture {} {LY} -20°C, sealed storage, away from moisture {} {} {LY} -20°C, sealed storage, away from moisture {} {} {} {LY} -20°C, sealed storage, away from moisture {} {} {} {} {LY} -20°C, sealed storage, away from moisture {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture {} {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, sealed

药物吸收、分布、代谢与排泄(ADME)

Lipinski's Rule of 3
Y
Lipinski's Rule of 5
Y
H-bond Acceptors
2
Rotatable Bonds
0
H-bond Donors
0
LogP
2

系列性分类


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