(R)-(-)-3-CYCLOPENTYL-2-(4-METHANESULFONYL-PHENYL)-N-THIAZOL-2-YL-PROPIONAMIDE

CAS 300353-13-3 MFCD12546328

化学结构图

300353-13-3
SMILES: CS(=O)(=O)C1=CC=C(C=C1)[C@@H](CC1CCCC1)C(=O)NC1=NC=CS1

化学属性

Mol. FormulaC18H22N2O3S2
Mol. Weight378.515

别名和识别编码

Chemical Name(R)-(-)-3-CYCLOPENTYL-2-(4-METHANESULFONYL-PHENYL)-N-THIAZOL-2-YL-PROPIONAMIDE
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相关文献及参考

  • [2]. Joseph Grimsby, et al. Allosteric activators of glucokinase: potential role in diabetes therapy. Science. 2003 Jul 18;301(5631):370-3.
  • [1]. Nancy-Ellen Haynes, et al. Discovery, structure-activity relationships, pharmacokinetics, and efficacy of glucokinase activator (2R)-3-cyclopentyl-2-(4-methanesulfonylphenyl)-N-thiazol-2-yl-propionamide (RO0281675). J Med Chem. 2010 May 13;53(9):3618-25.
  • [1]. Nancy-Ellen Haynes, et al. Discovery, structure-activity relationships, pharmacokinetics, and efficacy of glucokinase activator (2R)-3-cyclopentyl-2-(4-methanesulfonylphenyl)-N-thiazol-2-yl-propionamide (RO0281675). J Med Chem. 2010 May 13;53(9):3618-25.
  • [2]. Joseph Grimsby, et al. Allosteric activators of glucokinase: potential role in diabetes therapy. Science. 2003 Jul 18;301(5631):370-3.

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Glucokinase  (葡萄糖激酶)

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