2,8-Dimethyl-5-(2-(6-methylpyridin-3-yl)ethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole dihydrochloride 2,8-二甲基-5-(2-(6-甲基吡啶-3-基)乙基)-2,3,4,5-四氢-1H-吡啶并[4,3-b]吲哚 二盐酸盐

CAS 97657-92-6 MFCD17215933

化学结构图

97657-92-6
SMILES:

化学属性

Mol. Weight392.37 (anhydrous basis)
Mol. FormulaC21H25N3· 2HCl · xH2O

别名和识别编码

Synonym 2,8-Dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole dihydrochloride hydrate Dimebolin dihydrochloride hydrate Dimeboline dihydrochloride hydrate Dimebone dihydrochloride hydrate Dimebon dihydrochloride hydrate
Chemical Name2,8-Dimethyl-5-(2-(6-methylpyridin-3-yl)ethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole dihydrochloride
MDL NumberMFCD17215933
PubChem Substance ID329798824
Chemical Name Translation2,8-二甲基-5-(2-(6-甲基吡啶-3-基)乙基)-2,3,4,5-四氢-1H-吡啶并[4,3-b]吲哚 二盐酸盐
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分类

  • {SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, DIG-DY, Diversification Ready Pharma-Developed Compounds, Pfizer Compounds, 生物活性小分子, 细胞生物学
  • {SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, DIG-DY, Pfizer Compounds

相关文献及参考

  • [1]. Steele JW, et al. Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model. Mol Psychiatry. 2013 Aug;18(8):889-97.

安全信息

Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/39 Wear suitable protective clothing and eye/face protection 穿戴适当的防护服和眼睛/面保护;
GHS Symbol
Precautionary statements
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
WGK Germany3
Signal word Warning
Hazard Codes Xn
Risk Statements
  • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害

系列性分类


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