PD 149163 tetrahydrochloride hydrate

CAS N/A MFCD20527308

化学结构图

N/A
SMILES:

化学属性

Mol. Weight943.91 (anhydrous basis)
Mol. FormulaC42H71N9O6·4HCl · xH2O

别名和识别编码

Synonym N2-[(2S)-2,6-Diaminohexyl]-L-lysyl-L-prolyl-L-tryptophyl-3-methyl-L-valyl-L-Leucine ethyl ester tetrahydrochloride hydrate
MDL NumberMFCD20527308
Chemical NamePD 149163 tetrahydrochloride hydrate
PubChem Substance ID329823749
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分类

  • {SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuropeptides, Neurotensin - Receptor Agonists, Neurotensins, P-PH, Peptides and Proteins, Peptides for Cell Biology, Pfizer Compounds, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 蛋白质及衍生物
  • Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, GPCR Modulators, GPCR Proteins, Modulators and Antibodies,

相关文献及参考

  • Norman C, Grimond-Billa SK, Bennett GW, Cassaday HJ., A neurotensin agonist and antagonist decrease and increase activity, respectively, but do not preclude discrete cue conditioning. J. Psychopharmacol. 3 , 373-81, (2010) 摘要
  • Feifel D, Goldenberg J, Melendez G, Shilling PD., The acute and subchronic effects of a brain-penetrating, neurotensin-1 receptor agonist on feeding, body weight and temperature. Neuropharmacology 1 , 195-8, (2010) 摘要
  • Norman C, Beckett SR, Spicer CH, Ashton D, Langlois X, Bennett GW., Effects of chronic infusion of neurotensin and a neurotensin NT1 selective analogue PD149163 on amphetamine-induced hyperlocomotion. J. Psychopharmacol. 3 , 300-7, (2008) 摘要

安全信息

GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
WGK Germany3
Signal word Warning
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
Hazard Codes Xn
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Proteins and Derivatives - Biochemicals and Reagents
  4. Membrane Protein Biology Tools - Proteins and Derivatives
  5. GPCR Proteins, Modulators and Antibodies - Membrane Protein Biology Tools
  6. GPCR Modulators - GPCR Proteins, Modulators and Antibodies
  7. Neurotensin - Receptor Agonists - GPCR Modulators

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