PF-3644022 hydrate

CAS N/A MFCD21363374

化学结构图

N/A
SMILES:

化学属性

Mol. Weight374.46 (anhydrous basis)
Mol. FormulaC21H18N4OS · xH2O

别名和识别编码

Synonym (10R)-9,10,11,12-tetrahydro-10-methyl-3-(6-methyl-3-pyridinyl)-8H-[1,4]diazepino[5′,6′:4,5]thieno[3,2-f]quinolin-8-one hydrate (10R)-9,10,11,12-tetrahydro-10-methyl-3-(6-methyl-3-pyridinyl)-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one hydrate
MDL NumberMFCD21363374
Chemical NamePF-3644022 hydrate
PubChem Substance ID329823762
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分类

  • Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, MAPK-Activated Protein Kinase (MAPKAP Kinase), P, Pfizer Compounds, Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors
  • {SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Ind

相关文献及参考

  • Mourey RJ, Burnette BL, et al., A benzothiophene inhibitor of mitogen-activated protein kinase-activated protein kinase 2 inhibits tumor necrosis factor alpha production and has oral anti-inflammatory efficacy in acute and chronic models of inflammation. J. Pharmacol. Exp. Ther. 3 , 797-807, (2010)

安全信息

GHS Symbol
Precautionary statements
  • P305+P351+P338
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
WGK Germany3
Signal word Warning
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
Hazard Codes Xn
Risk Statements
  • R36 Irritating to eyes 刺激眼睛
  • R22 Harmful if swallowed 吞咽有害

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Kinase/Phosphatase Biology - Cell Signaling and Neuroscience
  5. Serine/Threonine Kinase Biology - Kinase/Phosphatase Biology
  6. Serine/Threonine Kinase Inhibitors - Serine/Threonine Kinase Biology
  7. MAPK-Activated Protein Kinase (MAPKAP Kinase) - Serine/Threonine Kinase Inhibitors

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