Corticosterone 21-Acetate 肾上腺酮 21-乙酯

CAS 1173-26-8 MFCD00010482

化学结构图

1173-26-8
SMILES: CC(=O)OCC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C

化学属性

Mol. FormulaC23H32O5
Mol. Weight389
Melting Point147.0 to 152.0 deg-C

别名和识别编码

Chemical NameCorticosterone 21-Acetate
CAS Number1173-26-8
Synonym (11?)-21-(Acetyloxy)-11-hydroxy-pregn-4-ene-3,20-dione 11-beta,21-Dihydroxypregn-4-ene-3,20-dione acetate 11BETA,21-DIHYDROXY-4-PREGNENE-3,20-DIONE 21-ACETATE 11BETA,21-DIHYDROXYPREGN-4-ENE-3,20-DIONE ACETATE 11beta,21-dihydroxypregn-4-ene-3,20-dione 21-acetate 11β,21-Dihydroxy-4-pregnene-3,20-dione 21-acetate, 4-Pregnene-11β,21-diol-3,20-dione 21-acetate 11β,21-dihydroxy-4-pregnene-3,20-dione 21-acetate 20-dione,11-beta,21-dihydroxy-pregn-4-ene-21-acetate 21-(Acetoxy)-11β-hydroxypregn-4-ene-3,20-dione 21-(acetyloxy)-11-hydroxy-20-dion(11-beta)-pregn-4-ene- 21-Acetoxy-11β-hydroxypregn-4-ene-3,20-dione 21-乙酸肾上腺酮 4-PREGNEN-11-BETA, 21-DIOL-3,20-DIONE 21-ACETATE 4-PREGNENE-11BETA,21-DIOL-3,20-DIONE 21-ACETATE CORTICOSTERONE 21-AC CORTICOSTERONE 21-ACETATE
MDL NumberMFCD00010482
PubChem Substance ID255846
Beilstein Registry Number8(3)3575
EC Number214-635-8
Reaxys-RN3225312
Merck Number2538
Chemical Name Translation肾上腺酮 21-乙酯
Wiswesser Line NotationL E5 B666 OV MUTJ A1 CQ E1 FV1OV1
LabNetwork Molecule IDLN01262509
InChIInChI=1S/C23H32O5/c1-13(24)28-12-20(27)18-7-6-17-16-5-4-14-10-15(25)8-9-22(14,2)21(16)19(26)11-23(17,18)3/h10,16-19,21,26H,4-9,11-12H2,1-3H3/t16-,17-,18+,19-,21+,22-,23-/m0/s1
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分类

  • {SNA} Alphabetical
  • Alphabetic, Analytical Standards, Analytical/Chromatography, C, CO - CZ, Chromatography, Clinical Standards, Hormones, Market Segments, Neats and Solutions, Standards for Food and Beverage Analysis, Standards for Pharma Clinical Forensic & Veterinary Analysis
  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Application Areas and Market Segments, C, CO - CZ, Chromatography, Clinical Standards, Hormones, Neats and Solutions, Pharma, 分析/色谱
  • {SNA} Alphabetic, Analytical Standards, Analytical/Chromatogra

产品应用

  • Corticosterone (C695700) derivative. An intermediate in the biosynthesis of aldosterone, isolated from the adrenal cortex.

相关文献及参考

  • Schmidt, M., et al.: Endocrinol., 150, 2709 (2009),
  • Bailey, M., et al.: J. Immunol., 182, 7888 (2009),
  • Brunton, P., et al.: J. Neurosci., 29, 6449 (2009),

安全信息

RTECSGM7820000
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P333+P313
  • P362+P364
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
Hazard Codes Xi
WGK Germany3
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Signal word Warning
Safety Statements
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Risk Statements
  • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 250 mg/kg
SEX/DURATION            : female 3 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - ovaries, fallopian tubes
   Reproductive - Maternal Effects - uterus, cervix, vagina
   Reproductive - Maternal Effects - menstrual cycle changes or disorders
REFERENCE :
   JRPFA4 Journal of Reproduction and Fertility.  (Biochemical Soc. Book Depot,
   POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK)  V.1-    1960-
   Volume(issue)/page/year: 51,309,1977

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 250 mg/kg
SEX/DURATION            : male 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
   JRPFA4 Journal of Reproduction and Fertility.  (Biochemical Soc. Book Depot,
   POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK)  V.1-    1960-
   Volume(issue)/page/year: 51,309,1977

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 800 mg/kg
SEX/DURATION            : female 11-14 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - abortion
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 6,313,1972

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 7200 mg/kg
SEX/DURATION            : female 11-14 day(s) after conception
TOXIC EFFEC

其他信息

  • Sigma Aldrich:1173-26-8(sigmaaldrich)
  • 21-乙酸肾上腺酮价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 C1479 肾上腺酮21-乙酯 Corticosterone 21-Acetate 500MG 1040元
  • MOL 文件:1173-26-8.mol
  • TCI Shanghai:肾上腺酮 21-乙酯 Corticosterone 21-Acetate,>;98.0%(LC)(1173-26-8)
  • 图谱信息:21-乙酸肾上腺酮(1173-26-8)红外图谱(IR2) 21-乙酸肾上腺酮(1173-26-8)红外图谱(IR1)

系列性分类

  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Market Segments - Analytical Standards
  4. Standards for Pharma Clinical Forensic & Veterinary Analysis - Market Segments
  5. Neats and Solutions - Standards for Pharma Clinical Forensic & Veterinary Analysis
  6. Hormones - Neats and Solutions
  1. Life Science 生命科学
  2. Biochemistry / Glyco-Chemistry
  3. Steroids

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