Phenethylamine, alpha,alpha-dimethyl-, hydrochloride Phentermine

CAS 1197-21-3 MFCD00058289

化学结构图

1197-21-3
SMILES: CC(C)(N)Cc1ccccc1.Cl

化学属性

Mol. FormulaC10H15N.ClH
Mol. Weight185.72

别名和识别编码

Chemical Namehydrochloride United States Pharmacopeia (USP) Reference Standard Phentermine Hydrochloride
CAS Number1197-21-3
Synonym alpha,alpha-Dimethylphenethylamine hydrochloride 1-Phenyl-2-methyl-2-aminopropane hydrochloride 2-Methyl-1-phenylpropan-2-amine hydrochloride 1-phenyl-2-methyl-2-aminopropanehydrochloride PHENTERMINE HYDROCHLORIDE--DEA*SCHEDULE IV ITEM ######## ALPHA,ALPHA-DIMETHYLPHENETHYLAMINE HYDROCHLORIDE 盐酸苯丁胺 phentermine hydrochloride methanol*solution Phenyl-t-butylamine hydrochloride (1,1-Dimethyl-2-phenyl)ethylamine hydrochloride alpha-Methylamphetamine hydrochloride Wilpo hydrochloride Phentermine hydrochloride alpha,alpha-Dimethylphenethylamine HCl Phtentermine hydrochloride PHENTERMINEHYDROCHLORIDE,USP alpha,alpha-dimethyl-phenethylaminhydrochloride MG 18370 Benzeneethanamine, alpha,alpha-dimethyl, hydrochloride α,α-Dimethylphenethylamine hydrochloride alpha-methylamphetaminehydrochloride benzeneethanamine,alpha,alpha-dimethyl,hydrochloride α,α-dimethylphenethylamine hydrochloride wilpohydrochloride Phentermine HCL Phentermine·hydrochloric acid PHENTERMINE HYDROCHLORIDE phenyl-t-butylaminehydrochloride
MDL NumberMFCD00058289
PubChem Substance ID70969
EC Number214-821-9
Alfabeta NameDIMETHYLPHENYLETHYLAMINEHYDROCHLORIDE 112---,
Chemical Name TranslationPhentermine
Merck Number13,7346
Wiswesser Line NotationZX1&1&1R &GH
InChIInChI=1S/C10H15N.ClH/c1-10(2,11)8-9-6-4-3-5-7-9;/h3-7H,8,11H2,1-2H3;1H
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分类

  • Amines
  • Aromatics
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • {SNA} Amphetamine, Analytical Standards, Analytical/Chromatography, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Chemical Structure, Chromatography, Drugs & Metabolites, Drugs of Abuse, Forensic and Veterinary Standards, Neat Compounds, Neurobiology, Neuroscience, P, Pharmacologicals, Stimulants

产品应用

  • Controlled substance (stimulant). Anorexic. An Amphetamine derivative.

相关文献及参考

  • Masheb, R., et al.: Obesity Res., 8, 638 (2000),
  • Fernandez-Lopez, J., et al.: Drugs, 62, 915 (2002),

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P301+P310
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
RTECSSH4950000
Signal word Danger
Hazard Codes T,Xi
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
Risk Statements
  • R25 Toxic if swallowed 吞咽有毒
UN Number UN 2811 6.1/PG 3
Restrict {} 精神药品 精麻类化学品
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 81 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APTOA6 Acta Pharmacologica et Toxicologica.  (Copenhagen, Denmark)  V.1-59,
   1945-86.  For publisher information, see PHTOEH  Volume(issue)/page/year:
   17,121,1960

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 188 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   3,256,1961

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 154 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   3,256,1961

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 15 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 79,187,1943

其他信息

  • Hazard Note:Irritant
  • Sigma Aldrich:1197-21-3(sigmaaldrich)
  • MOL 文件:1197-21-3.mol

系列性分类


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