2-(1,2-Dichloroethyl)pyridine hydrochloride

CAS 1532-19-0 MFCD01532190

化学结构图

1532-19-0
SMILES: Cl.ClCC(Cl)c1ccccn1

化学属性

Mol. Weight212.51
Mol. FormulaC7H7Cl2N.ClH

别名和识别编码

Wiswesser Line NotationT6NJ BYG1G &GH
Chemical NamePyridine, 2-(1,2-dichloroethyl)-, hydrochloride
Synonym 2-(1,2-Dichloroethyl)pyridine hydrochloride CLEP 2-(alpha,beta-Dichlorethyl)-pyridine hydrochloride
CAS Number1532-19-0
InChIKeyZMOQBTRTDSZZRU-UHFFFAOYSA-N
PubChem Substance ID102643
InChIInChI=1S/C7H7Cl2N.ClH/c8-5-6(9)7-3-1-2-4-10-7;/h1-4,6H,5H2;1H
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安全信息

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 8580 mg/kg/89W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Gastrointestinal - tumors
REFERENCE :
   PAACA3 Proceedings of the American Association for Cancer Research. (Waverly
   Press, 428 E. Preston St., Baltimore, MD 21202)  V.1-    1954-
   Volume(issue)/page/year: 9,28,1968

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 19 gm/kg/37W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Gastrointestinal - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   PAACA3 Proceedings of the American Association for Cancer Research. (Waverly
   Press, 428 E. Preston St., Baltimore, MD 21202)  V.1-    1954-
   Volume(issue)/page/year: 9,28,1968

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Multiple routes
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2640 mg/kg/37W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Gastrointestinal - tumors
   Liver - tumors
REFERENCE :
   GANMAX Gann Monograph.  (Tokyo, Japan)  No.1-10, 1966-71.  For publisher
   information, see GMCRDC.  Volume(issue)/page/year: 3,51,1966

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5940 mg/kg/84W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - tumors
REFERENCE :
   GANMAX Gann Monograph.  (Tokyo, Japan)  No.1-10, 1966-71.  For publisher
   information, see GMCRDC.  Volume(issue)/page/year: 3,51,1966

RTECSUS8650000

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