Cetamiphen

CAS 1870-65-1 MFCD01737368

化学结构图

1870-65-1
SMILES: CCC(C(=O)O)c1ccccc1.NCCO

化学属性

Mol. FormulaC10H12O2.C2H7NO
Mol. Weight225.32

别名和识别编码

Chemical NameCetamiphen
InChIKeyOBBCMAHJFIJQIK-UHFFFAOYSA-N
Synonym 2-phenylbutyrate-ethanolamine salt Benzeneacetic acid, alpha-ethyl-, compd. with 2-aminoethanol (1:1) Cetamiphen Cetimiphen Phenexol Tstamifen cetamiphen
CAS Number1870-65-1
PubChem Substance ID15858
InChIInChI=1S/C10H12O2.C2H7NO/c1-2-9(10(11)12)8-6-4-3-5-7-8;3-1-2-4/h3-7,9H,2H2,1H3,(H,11,12);4H,1-3H2
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安全信息

RTECSET5958500 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1600 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - somnolence (general depressed activity)
   Behavioral - irritability
REFERENCE :
   FATOBP Farmakologiya i Toksikologiya (Kiev).  Pharmacology and Toxicology.
   (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii,
   Kiev, USSR)  No.1-    1964-  Volume(issue)/page/year: 9,107,1974

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   FATOBP Farmakologiya i Toksikologiya (Kiev).  Pharmacology and Toxicology.
   (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii,
   Kiev, USSR)  No.1-    1964-  Volume(issue)/page/year: 9,107,1974

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1440 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - somnolence (general depressed activity)
   Behavioral - irritability
REFERENCE :
   FATOBP Farmakologiya i Toksikologiya (Kiev).  Pharmacology and Toxicology.
   (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii,
   Kiev, USSR)  No.1-    1964-  Volume(issue)/page/year: 9,107,1974

TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIE

系列性分类

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