Phosphinic amide, P,P-bis(1-aziridinyl)-N-propyl-

CAS 2275-81-2 MFCD N/A

化学结构图

2275-81-2
SMILES: CCCNP(=O)(N1CC1)N1CC1

化学属性

Mol. Weight189.23
Mol. FormulaC7H16N3OP

别名和识别编码

Chemical NamePhosphinic amide, P,P-bis(1-aziridinyl)-N-propyl-
Synonym P,P-Bis(1-aziridinyl)-N-propylphosphinic amide Propylamino-bis(1-aziridinyl)phosphine oxide P,P-Bis(1-aziridinyl)-N-propylaminophosphine oxide Phosphine oxide, bis(1-aziridinyl)propylamino- ENT 51253
CAS Number2275-81-2
InChIKeyRJINYDJYHIWLRL-UHFFFAOYSA-N
PubChem Substance ID145658
InChIInChI=1S/C7H16N3OP/c1-2-3-8-12(11,9-4-5-9)10-6-7-10/h2-7H2,1H3,(H,8,11)
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安全信息

RTECSSZ5832000 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 28,70,1965

TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE       : Parenteral
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 500 pmol/L
REFERENCE :
   IMSUAI Industrial Medicine and Surgery.  (Northbrook, IL)  V.18-42, 1949-73.
    For publisher information, see IOHSA5.  Volume(issue)/page/year:
   38,442,1969

TYPE OF TEST            : Phage inhibition capacity
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 2300 umol/L
REFERENCE :
   HEREAY Hereditas (Lund, Sweden).  (Gjoerloffsgatan 121, S-261 34 Landskrona,
   Sweden)  V.1-    1947-  Volume(issue)/page/year: 68,245,1971

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Yeast - Schizosaccharomyces pombe
DOSE/DURATION           : 70 mmol/L
REFERENCE :
   HEREAY Hereditas (Lund, Sweden).  (Gjoerloffsgatan 121, S-261 34 Landskrona,
   Sweden)  V.1-    1947-  Volume(issue)/page/year: 68,245,1971

TYPE OF TEST            : Dominant lethal test
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 500 ug/kg
REFERENCE :
   FOBLAN Folia Biologica (Prague).  (Academic Press Inc. Ltd., 24-28 Oval Rd.,
   London NW1 7DX, UK) V.1-    1955-  Volume(issue)/page/year: 20,1,1974

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 33 umol/L
REFERENCE :
   HEREAY Hereditas (Lund, Sweden).  (Gjoerloffsgatan 121, S-261 34 Landskrona,
   Sweden)  V.1-    1947-  Volume(issue)/page/year: 68,255,1971

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 500 ug/kg
SEX/DURATION            : male 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   FOBLAN Folia Biologica (Prague).  (Academic Press Inc. Ltd., 24-28 Oval Rd.,
   London NW1 7DX, UK) V.1-    1955-  Volume(issue)/page/year: 20,1,1974

系列性分类

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