Piritramide
CAS 302-41-0 MFCD00864268
化学结构图
SMILES:
化学属性
| Mol. Formula | C27H34N4O |
|---|---|
| Mol. Weight | 430.65 |
别名和识别编码
| Chemical Name | (1,4'-Bipiperidine)-4'-carboxamide,1'-(3-cyano-3,3-diphenylpropyl)- |
|---|---|
| CAS Number | 302-41-0 |
| Synonym | Piritramide Dipiritramide ######## R 3365 1'-(3-Cyano-3,3-diphenylpropyl)(1,4'-bipiperidine)-4'-carboxamide Piridolan Pirinitramide 2,2-Diphenyl-4-(4-piperidino-4-carbamoylpiperidino)butyronitrile Dipidolor |
| Beilstein Registry Number | 0501362 |
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分类
- Amines
- Aromatics
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
- It is a synthetic opioid commonly used in Germany and Austria for the analgesia of pediatric patients.
相关文献及参考
- Anand, K., et al.: J. Pediatr. Surg., 23, 297 (1988),
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : >40 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 13,513,1961
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 30700 ug/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - respiratory depression REFERENCE : FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 54(5),59,1991
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 280 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - respiratory depression REFERENCE : JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/pa
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >320 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 13,513,1961
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOS
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