Ethylnorepinephrine hydrochloride α-乙基去甲肾上腺素盐酸

CAS 3198-07-0 MFCD00135054

化学结构图

3198-07-0
SMILES: CCC(N)C(O)c1ccc(O)c(O)c1.Cl

化学属性

Mol. FormulaC10H15NO3.ClH
Mol. Weight233.72

别名和识别编码

Chemical NameBenzyl alcohol, alpha-(1-aminopropyl)-3,4-dihydroxy-,hydrochloride
CAS Number3198-07-0
Synonym 1-(3,4-Dihydroxyphenyl)-1-hydroxy-2-aminobutane hydrochloride 1-(3,4-Dihydroxyphenyl)-2-amino-1-butanol hydrochloride 4-(2-Amino-1-hydroxybutyl)-1,2-benzenediol Hydrochloride ?-(1-Aminopropyl)protocatechuyl Alcohol Hydrochloride Bronkephrine Butanefrine hydrochloride Butanephrine Hydrochloride Ethyl norepinephrine hydrochloride Ethylnoradrenaline hydrochloride Ethylnorsuprarenin hydrochloride alpha-(1-Aminopropyl)protocatechuyl alcohol hydrochloride alpha-Ethylnorepinephrine hydrochloride butanephrine ethylnorepinephrine ethylnorepinephrine hydrochloride
Chemical Name Translationα-乙基去甲肾上腺素盐酸
Wiswesser Line NotationZY2&YQR CQ DQ &GH
PubChem Substance ID18900
InChIInChI=1S/C10H15NO3.ClH/c1-2-7(11)10(14)6-3-4-8(12)9(13)5-6;/h3-5,7,10,12-14H,2,11H2,1H3;1H
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分类

  • Pharmaceuticals
  • Intermediates & Fine Chemicals,

产品应用

  • A bronchodilator.

相关文献及参考

  • Daly, J. W

安全信息

RTECSDN7875000 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Human
DOSE/DURATION           : 36 ug/kg
TOXIC EFFECTS :
   Cardiac - change in rate
   Vascular - pulse pressure increase
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 81,269,1944

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Human
DOSE/DURATION           : 9 ug/kg
TOXIC EFFECTS :
   Cardiac - change in rate
   Vascular - BP lowering not characterized in autonomic section
   Vascular - pulse pressure increase
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 81,269,1944

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 117 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 81,269,1944

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 160 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 81,269,1944

系列性分类

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