4(3H)-Quinazolinone, 3-(m-chlorophenyl)-2-methyl-

CAS 340-94-3 MFCD00340943

化学结构图

340-94-3
SMILES: Cc1[n]c2ccccc2c(=O)[n]1-c1cc(Cl)ccc1

化学属性

Mol. FormulaC15H11ClN2O
Mol. Weight270.73

别名和识别编码

Wiswesser Line NotationT66 BN DNVJ C1 DR BG
Chemical Name4(3H)-Quinazolinone, 3-(m-chlorophenyl)-2-methyl-
Synonym Ro 345 3-(m-Chlorophenyl)-2-methyl-4(3H)-quinazolinone 2-Methyl-3-(3'-chlorphenyl)-4-chinazolinon
CAS Number340-94-3
Beilstein Registry Number0228739
InChIKeyFRZCXJROWSIXPR-UHFFFAOYSA-N
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安全信息

RTECSVA2974000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 460 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   PHARAT Pharmazie.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
   Berlin DDR-1020, Ger. Dem. Rep.)  V.1-    1946-  Volume(issue)/page/year:
   17,616,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1200 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 22,129,1967

系列性分类

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