Iodophthalein 3,3-双(4-羟基-3,5-二碘苯基)异苯并呋喃-1(3H)-酮

CAS 386-17-4 MFCD00001614

化学结构图

386-17-4
SMILES: O=C1OC(c2cc(I)c(O)c(I)c2)(c2cc(I)c(O)c(I)c2)c2ccccc21

化学属性

Mol. FormulaC20H10I4O4
Mol. Weight821.91
Melting Point268 °C
Boiling Point607.5±55.0 °C at 760 mmHg

别名和识别编码

Chemical Name3,3-Bis(4-Hydroxy-3,5-Diiodophenyl)Isobenzofuran-1(3H)-One
MDL NumberMFCD00001614
CAS Number386-17-4
PubChem Substance ID67846
EC Number206-857-9
Reaxys-RN351654
Beilstein Registry Number18(3/4)1949
Merck Number5038
Synonym 3,3-Bis(4-hydroxy-3,5-diiodophenyl)isobenzofuran-1(3H)-one {LY} 3,3-Bis(4-hydroxy-3,5-diiodophenyl)isobenzofuran-1(3H)-one iodophthalein iodophthalein, 131I-labeled iodophthalein, disodium salt {} {LY} 3,3-Bis(4-hydroxy-3,5-diiodophenyl)isobenzofuran-1(3H)-one {} {} {LY} 3,3-Bis(4-hydroxy-3,5-diiodophenyl)isobenzofuran-1(3H)-one {} {} {} {LY} 3,3-Bis(4-hydroxy-3,5-diiodophenyl)isobenzofuran-1(3H)-one {} {} {} {} {LY} 3,3-Bis(4-hydroxy-3,5-diiodophenyl)isobenzofuran-1(3H)-one {} {} {} {} {} {LY} 3,3-Bis(4-hydroxy-3,5-diiodophenyl)isobenzofuran-1(3H)-one {} {} {} {} {} {} {LY} 3,3-Bis(4-hydroxy-3,5-diiodophenyl)isobenzofuran-1(3H)-one {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {LY} 3,3-Bis(4-hydroxy-3,5-diiodophenyl)isobenzofuran-1(3H)-one {} {} {} {} {} {} {} {} {LY} 3,3-Bis(4-hydroxy-3,5-diiodophenyl)isobenzofuran-1(3H)-one {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 3,3-Bis(4-hydroxy-3,5-diiodophenyl)isobenzofuran-1(3
Chemical Name Translation3,3-双(4-羟基-3,5-二碘苯基)异苯并呋喃-1(3H)-酮
InChIInChI=1S/C20H10I4O4/c21-13-5-9(6-14(22)17(13)25)20(10-7-15(23)18(26)16(24)8-10)12-4-2-1-3-11(12)19(27)28-20/h1-8,25-26H
LabNetwork Molecule IDLN01746402
Canonical SMILESO=C1OC(C2=CC(I)=C(O)C(I)=C2)(C3=CC(I)=C(O)C(I)=C3)C4=C1C=CC=C4
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安全信息

RTECSSM8397000
WGK Germany2
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Signal word
Hazard statements
  • H303 May be harmfully swallowed 吞食可能有害
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
  • H351 Suspected of causing cancer 怀疑致癌
  • H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
Precautionary statements
  • P203
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P318
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P332+P317
  • P337+P317
  • P362+P364
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 310 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - acute pulmonary edema
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   KLWOAZ Klinische Wochenscrift.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.1-    1922-  Volume(issue)/page/year:
   20,125,1941

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - duck
DOSE/DURATION           : 79200 ug/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
REFERENCE :
   VETNAL Veterinariya.  Veterinary Science.  (V/O Mezhdunarodnaya Kniga,
   113095 Moscow, USSR) V.1-    1924-  Volume(issue)/page/year: 54(5),64,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2800 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Behavioral - muscle contraction or spasticity
REFERENCE :
   KLWOAZ Klinische Wochenscrift.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.1-    1922-  Volume(issue)/page/year:
   20,125,1941

Storage condition 2-8°C, protect from light, stored under nitrogen {LY} 2-8°C, protect from light, stored under nitrogen {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitr

系列性分类


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