Cytosine, 1-beta-D-arabinofuranosyl-5-fluoro-

CAS 4298-10-6 MFCD00036765

化学结构图

4298-10-6
SMILES: Nc1nc(=O)n([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)cc1F

化学属性

Mol. FormulaC9H12FN3O5
Mol. Weight261.24

别名和识别编码

Chemical NameCytosine, 1-beta-D-arabinofuranosyl-5-fluoro-
MDL NumberMFCD00036765
Synonym Arafluorocytosine Ara-FC 5-Fluorocytosine arabinoside 1-beta-D-Arabinofuranosyl-5-fluorocytosine 2(1H)-Pyrimidinone, 4-amino-1-beta-D-arabinofuranosyl-5-fluoro-
CAS Number4298-10-6
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安全信息

WGK Germany3
RTECSHA5450000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ADTEAS Advances in Teratology.  (New York, NY)  V.1-5, 1966-72.
   Discontinued.  Volume(issue)/page/year: 3,181,1968

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 380 nmol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   26,1661,1966

TYPE OF TEST            : DNA inhibition
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 10 mg/kg
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   29,1790,1969

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 3800 nmol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   26,1661,1966

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