Metenolone Acetate 美替诺龙醋酸酯

CAS 434-05-9 MFCD00864181

化学结构图

434-05-9
SMILES: CC(=O)O[C@H]1CC[C@H]2[C@@H]3CC[C@H]4CC(=O)C=C(C)[C@]4(C)[C@H]3CC[C@]12C

化学属性

Mol. FormulaC22H32O3
Mol. Weight344.54

别名和识别编码

Chemical NameMetenolone Acetate
CAS Number434-05-9
Synonym ######## 1(5-ALPHA)-ANDROSTEN-1-BETA-METHYL-17-BETA-OL-3-ONE ACETATE 1-Methyl-17b-hydroxy-5a-androst-1-en-3-one acetate 1-Methyl-17b-hydroxy-5a-androst-1-en-3-one-17b-acetate 1-Methyl-5a-androst-1-en-17b-ol-3-one acetate 17-(acetyloxy)-1-methyl-,(5-alpha,17-beta)-androst-1-en-3-on 17-beta-Hydroxy-1-methyl-5-alpha-androst-1-en-3-one acetate 17-beta-hydroxy-1-methyl-5-alpha-androst-1-en-3-onacetate 17-beta-hydroxy-1-methyl-5-alpha-androst-1-en-3-oneacetate 17b-Hydroxy-1-methyl-5a-androst-1-en-3-one acetate 17b-Hydroxy-1-methyl-5alpha-androst-1-en-3-one acetate 17b-hydroxy-1-methyl-5alpha-androst-1-en-3-one acetate 17β-羟基-1-甲基-5α-雄甾-1-烯-3-酮-17-醋酸酯 5a-Androst-1-en-3-one, 17b-hydroxy-1-methyl-, acetate (6CI, 8CI) Androst-1-en-3-one, 17-(acetyloxy)-1-methyl-, (5-alpha,17-b
EC Number207-097-0
MDL NumberMFCD00864181
Chemical Name Translation美替诺龙醋酸酯
Wiswesser Line NotationL E5 B666 OV LUTJ A1 E1 FOV1 K1
PubChem Substance ID252372
InChIInChI=1S/C22H32O3/c1-13-11-16(24)12-15-5-6-17-18-7-8-20(25-14(2)23)21(18,3)10-9-19(17)22(13,15)4/h11,15,17-20H,5-10,12H2,1-4H3/t15-,17-,18-,19-,20-,21-,22-/m0/s1
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分类

  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Steroids

产品应用

  • Methenolone acetate is an anabolic steroid.

相关文献及参考

  • Schiffer, M., et al.: J. Clin. Invest., 108, 807 (2001),
  • Okuyama, S., et al.: Clin. Nephrol., 68, 412 (2007),
  • Sjoqvist, F., et al.: Lancet, 371, 1872 (2008),

安全信息

RTECSBV8408500 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,835,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,835,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,835,1982

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 60 mg/kg
SEX/DURATION            : female 17-20 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - urogenital system
REFERENCE :
   AVBIB9 Advances in the Biosciences.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1967-  Volume(issue)/page/year:
   13,71,1974

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 200 mg/kg
SEX/DURATION            : male 10 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland,
   accessory glands
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 14,330,1964

Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H351 Suspected of causing cancer 怀疑致癌
  • H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
  • H362 May cause harm to breast-fed children 可能对母乳喂养的婴儿造成伤害
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P263 Avoid contact during pregnancy/while nursing. 怀孕/哺乳期间避免接触。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P301+P312
  • P308+P313
  • P330 Rinse mouth. 漱口
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....

其他信息

  • MOL 文件:434-05-9.mol

系列性分类

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