3,3'-Dihydroxy-beta,beta-carotene-4,4'-dione 3,3'-二羟基-beta,beta-胡萝卜素-4,4'-二酮

CAS 472-61-7 MFCD00672621

化学结构图

472-61-7
SMILES: CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)C(=O)[C@@H](O)CC2(C)C)C(C)(C)C[C@H](O)C1=O

化学属性

Mol. FormulaC40H52O4
Mol. Weight596.84
Melting Point215-216°C
Density1.071

别名和识别编码

Chemical Name3,3'-Dihydroxy-beta,beta-carotene-4,4'-dione
CAS Number472-61-7
Synonym (3S,3'S)-3,3'-Dihydroxy-β,β-Carotene-4,4'-dione 3,3'-Dihydroxy-beta,beta-carotene-4,4'-dione 3,3'-Dihydroxy-β-carotene-4,4'-dione 3,3'-二羟基-beta,beta-胡萝卜素-4,4'-二酮 3,3?-Dhydroxy-4,4?-diketo-?-carotene 3,3?-Dihydroxy-?,?-carotene-4,4?-dione 3,3′-二羟基-β,β-胡萝卜素-4,4′-二酮 3,3′-二羟基-β,β-胡萝卜素-4,4′-二酮 E-astaxanthin Ovoester astaxanthin astaxanthine trans-Astaxanthin 虾青素
MDL NumberMFCD00672621
PubChem Substance ID5281224
EC Number207-451-4
Chemical Name Translation3,3'-二羟基-beta,beta-胡萝卜素-4,4'-二酮
InChIInChI=1S/C40H52O4/c1-27(17-13-19-29(3)21-23-33-31(5)37(43)35(41)25-39(33,7)8)15-11-12-16-28(2)18-14-20-30(4)22-24-34-32(6)38(44)36(42)26-40(34,9)10/h11-24,35-36,41-42H,25-26H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,27-15+,28-16+,29-19+,30-20+/t35-,36-/m0/s1
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分类

  • Pharmaceuticals
  • {SNA} A, AR to AZ, All alphabetical sorted, Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Carotenoids, Chemical Class,
  • {SNA} AN-AZ, Bioactive Small Molecule Alphabetical Index, 一氧化氮和细胞应激, 抗氧化剂和细胞保护剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞应激, 细胞生物学
  • {SNA} A, AR to AZ, All alphabetical sorted, Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Chemical Class, Chromatography, Colors,

产品应用

  • 虾青素是在海藻、红酵母和许多植物和动物来源中发现的?强效类胡萝卜素抗氧化剂。动物试验表明,它可降低血糖?并改善糖尿病代谢综合征的若干指标。可改善高血型模型?的血流和血管张力。体外研究表明,它上调间隙联接蛋白? 43,可用于化学防癌。

相关文献及参考

  • [2]. Desheng Fu, et al. Effect of astaxanthin on retinal pigment epithelial cells in high glucose: an invitro study. Biomedical Research 2017; 28 (15): 6839-6843.
  • [3]. Rachel K Johnston, et al. Effects of astaxanthin on Brachionus manjavacas (Rotifera) population growth. Aquaculture Research. 2018;49:2278–2287.
  • Bertram, J.S., et al.: Biochem. Biophys. Acta, 1740, 170 (2005),
  • Schroeder, W.A., et al.: J. Biol. Chem., 270, 18374 (1995),
  • [1]. Yang Y, et al. Epigenetic CpG Methylation of the Promoter and Reactivation of the Expression of GSTP1 by Astaxanthin in Human Prostate LNCaP Cells. AAPS J. 2017 Mar;19(2):421-430.
  • [1]. Yang Y, et al. Epigenetic CpG Methylation of the Promoter and Reactivation of the Expression of GSTP1 by Astaxanthin in Human Prostate LNCaP Cells. AAPS J. 2017 Mar;19(2):421-430.
  • [2]. Desheng Fu, et al. Effect of astaxanthin on retinal pigment epithelial cells in high glucose: an invitro study. Biomedical Researc

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
GHS Symbol
Storage condition ?20°C保存,避光保存 储存温度 -20°C ,避光保存
Hazard statements
  • H413 Maycauselonglastingharmfuleffectstoaquaticlife 可能对水生生物造成长期持续有害影响。
Precautionary statements
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....

系列性分类


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