Morphinan-3,6-alpha-diol, 4,5-alpha-epoxy-17-methyl-

CAS 509-60-4 MFCD00190622

化学结构图

509-60-4
SMILES: CN1CC[C@@]23[C@H]4OC5C2=C(C[C@@H]1[C@@H]3CC[C@@H]4O)C=CC=5O |&1:4,5,11,12,15|

化学属性

Mol. FormulaC17H21NO3
Mol. Weight287.39

别名和识别编码

Chemical NameMorphinan-3,6-alpha-diol, 4,5-alpha-epoxy-17-methyl-
CAS Number509-60-4
Synonym Dihydromorfin 7,8-Dihydromorphine alpha-Dihydromorphine Paramorphan (5?,6?)-4,5-Epoxy-17-methylmorphinan-3,6-diol NSC 117865 6-alpha-Hydromorphol Dihydromorphine Paramorfan 6?-Hydromorphol Morphine, dihydro- Hydromorphine Par 6?-7,8-Dihydromorphine DHM
Wiswesser Line NotationT B6566 B6/CO 4ABBC R BX HO PN GHT&&TTJ FQ JQ P1
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分类

  • Chiral Reagents
  • Metabolites & Impurities
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Dihydromorphine is a metabolite of Hydromorphone (H714650).

相关文献及参考

  • Bogusz, M., et al.: J. Anal. Toxicol., 22, 549 (1998),
  • Polettini, A., et al.: Forensic Sci. Int., 153, 23 (2005),
  • Miller, E., et al.: J. Anal. Toxicol., 30, 441 (2006),

安全信息

RTECSQC8945000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 6,146,1951

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 80 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 6,146,1951

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