TREMORINE DIHYDROCHLORIDE

CAS 51-73-0 MFCD00012719

化学结构图

51-73-0
SMILES: C(#CCN1CCCC1)CN1CCCC1

化学属性

Mol. FormulaC12H20N2
Mol. Weight192.34

别名和识别编码

Chemical NamePyrrolidine, 1,1'-(2-butynylene)di-
Synonym 1,4-Dipyrrolidino-2-butyne Tremorine 1,4-Dipyrrolidine-2-butyne 2-Butyne, 1,4-bis(1-pyrrolidinyl)- Biofermin 1,4-Dipyrrolidinyl-2-butyne Dipyrrolidine, 1,1'-(2-butynylene)-
Wiswesser Line NotationT5NTJ A2UU2- AT5NTJ
CAS Number51-73-0
Beilstein Registry Number0006119
PubChem Substance ID5534
InChIInChI=1S/C12H20N2/c1-2-8-13(7-1)11-5-6-12-14-9-3-4-10-14/h1-4,7-12H2
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安全信息

RTECSUY0175000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 112 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#12070

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 58 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Gastrointestinal - hypermotility, diarrhea
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   56(3),83S,1960

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Gastrointestinal - changes in structure or function of salivary glands
   Gastrointestinal - hypermotility, diarrhea
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 135,447,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - wild bird species
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicol

系列性分类


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