Histamine, monohydrochloride 组胺盐酸盐

CAS 55-36-7 MFCD N/A

化学结构图

55-36-7
SMILES:

化学属性

Mol. Weight366.39
Mol. FormulaC5H9N3.xClH

别名和识别编码

Wiswesser Line NotationT5M CNJ D2Z &GH
Chemical NameHistamine, monohydrochloride
Synonym Chlorhydrate d'histamine Histamine, monohydrochloride 1H-Imidazole-4-ethanamine, monohydrochloride
CAS Number55-36-7
Chemical Name Translation组胺盐酸盐
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安全信息

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1140 mg/kg/28W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Gastrointestinal - tumors
REFERENCE :
   BAFEAG Bulletin de l'Association Francaise pour l'Etude du Cancer.  (Paris,
   France)  V.1-52, 1908-65. For publisher information, see BUCABS.
   Volume(issue)/page/year: 36,305,1949

RTECSNI3505000 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intracerebral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 865 ug/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ZIETA2 Zeitschrift fuer Immunitaetsforschung und Experimentelle Therapie.
   (Stuttgart, Fed. Rep. Ger.)  1924-62.  For publisher information, see
   ZIEKBA.  Volume(issue)/page/year: 60,222,1929

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ZIETA2 Zeitschrift fuer Immunitaetsforschung und Experim

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TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 2273 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ZIETA2 Zeitschrift fuer Immunitaetsforschung und Experimentelle Therapie.
   (Stuttgart, Fed. Rep. Ger.)  1924-62.  For publisher information, see
   ZIEKBA.  Volume(issue)/page/year: 60,222,1929

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ZIETA2 Zeitschrift fuer Immunitaetsforschung und Experimentelle Therapie.
   (Stuttgart, Fed. Rep. Ger.)  1924-62.  For publisher information, see
   ZIEKBA.  Volume(issue)/page/year: 60,222,1929

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED

系列性分类

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