Mefenorex hydrochloride

CAS 5586-87-8 MFCD00242765

化学结构图

5586-87-8
SMILES: CC(Cc1ccccc1)NCCCCl.Cl

化学属性

Mol. FormulaC12H18ClN.ClH
Mol. Weight248.22

别名和识别编码

Chemical NamePhenethylamine, N-(3-chloropropyl)-alpha-methyl-,hydrochloride
CAS Number5586-87-8
Synonym Benzeneethanamine, N-(3-chloropropyl)-alpha-methyl-, hydrochloride Incital Mefenorex hydrochloride N-(3-Chloropropyl)-1-methyl-2-phenylethylamine Hydrochloride N-(3-Chloropropyl)-?-methylbenzeneethanamine Hydrochloride N-(3-Chloropropyl)-alpha-methylphenethylamine hydrochloride N-(3-Chlorpropyl)-1-methyl-2-phenyl-aethylamin-hydrochlorid N-Chloropropylamphetamine Hydrochloride NSC 133749 Pondi Pondinil Ro 4-5282 chloropropylamphetamine mefenorex mefenorex hydrochloride mefenorex, (+-)-isomer
Wiswesser Line NotationG3MY1&1R &GH
PubChem Substance ID21776
InChIInChI=1S/C12H18ClN.ClH/c1-11(14-9-5-8-13)10-12-6-3-2-4-7-12;/h2-4,6-7,11,14H,5,8-10H2,1H3;1H
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分类

  • Amines
  • Aromatics
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • This is a controlled substance (stimulant). Anorexic.

相关文献及参考

  • Netter, P., et al.: Arzneim.-Forsch., 28, 1310 (1978); Rendic, S., et al.: Eur. J. Drug Metab. Pharmacokinet., 19, 107 (1994);

安全信息

RTECSSH2100000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 144 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,356

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 180 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 19,748,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 49 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,356,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 230 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 19,748,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/

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