2-Amino-8-Hydroxy-1H-Purin-6(7H)-One 2-氨基-6,8-二羟基嘌呤

CAS 5614-64-2 MFCD00005564

化学结构图

5614-64-2
SMILES: Nc1nc2[nH]c(=O)[nH]c2c(=O)[nH]1

化学属性

Mol. FormulaC5H5N5O2
Mol. Weight167.13

别名和识别编码

Chemical Name2-Amino-8-Hydroxy-1H-Purin-6(7H)-One
MDL NumberMFCD00005564
CAS Number5614-64-2
Synonym 2-氨基-6,8-嘌呤二醇 8-羟基鸟嘌呤
EC Number227-035-6
Chemical Name Translation2-氨基-6,8-二羟基嘌呤
InChIKeyCLGFIVUFZRGQRP-UHFFFAOYSA-N
PubChem Substance ID135420630
InChIInChI=1S/C5H5N5O2/c6-4-8-2-1(3(11)10-4)7-5(12)9-2/h(H5,6,7,8,9,10,11,12)
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相关文献及参考

  • [2]. Floyd RA, et al. The role of 8-hydroxyguanine in carcinogenesis. Carcinogenesis. 1990 Sep;11(9):1447-50.
  • [3]. Cheng KC, et al. 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G----T and A----C substitutions. J Biol Chem. 1992 Jan 5;267(1):166-72.
  • [1]. Arai T, et al. High accumulation of oxidative DNA damage, 8-hydroxyguanine, in Mmh/Ogg1 deficient mice by chronic oxidative stress. Carcinogenesis. 2002 Dec;23(12):2005-10.
  • [1]. Arai T, et al. High accumulation of oxidative DNA damage, 8-hydroxyguanine, in Mmh/Ogg1 deficient mice by chronic oxidative stress. Carcinogenesis. 2002 Dec;23(12):2005-10.
  • [2]. Floyd RA, et al. The role of 8-hydroxyguanine in carcinogenesis. Carcinogenesis. 1990 Sep;11(9):1447-50.
  • [3]. Cheng KC, et al. 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G----T and A----C substitutions. J Biol Chem. 1992 Jan 5;267(1):166-72.

安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Signal word Warning

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Endogenous Metabolite  (内源性代谢物)

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