Medronate Tetrasodium

CAS 6145-29-5 MFCD N/A

化学结构图

6145-29-5
SMILES: O=P([O-])([O-])CP(=O)([O-])[O-].[Na+].[Na+].[Na+].[Na+]

化学属性

Mol. Weight263.93
Mol. FormulaCH2O6P2.4Na

别名和识别编码

Synonym Methylenediphosphonic acid, sodium salt Methanebisphosphonic acid, sodium salt Sodium methylenediphosphonate MDP sodium Methylenebisphosphonic acid tetrasodium salt Methylenebis(phosphonic acid) sodium salt Medronic acid, sodium salt Methanediphosphonic acid, sodium salt
Chemical NamePhosphonic acid, methylenebis-, tetrasodium salt
CAS Number6145-29-5
PubChem Substance ID160810
InChIInChI=1S/CH6O6P2.4Na/c2-8(3,4)1-9(5,6)7;;;;/h1H2,(H2,2,3,4)(H2,5,6,7);;;;/q;4*+1/p-4
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安全信息

RTECSSZ5383000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - structural or functional change in trachea
   or bronchi
   Liver - other changes
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan)  V.1-    1972-
   Volume(issue)/page/year: 5,2467,1977

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 67 mg/kg
TOXIC EFFECTS :
   Cardiac - other changes
   Behavioral - muscle contraction or spasticity
   Liver - other changes
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan)  V.1-    1972-
   Volume(issue)/page/year: 5,2467,1977

系列性分类

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