Phenyltoloxamine hydrochloride

CAS 6152-43-8 MFCD N/A

化学结构图

6152-43-8
SMILES:

化学属性

Mol. Weight291.85
Mol. FormulaC17H21NO.ClH

别名和识别编码

Wiswesser Line Notation1N1&2OR B1R &GH
Chemical NamePhenyltoloxamine hydrochloride
Synonym Ethylamine, N,N-dimethyl-2-((alpha-phenyl-o-tolyl)oxy)-, hydrochloride HL 2153 N-(2'-Dimethylaminoaethyl)-(o-benzylphenol)-aether hydrochlorid Phenyltoloxamine hydrochloride N,N-Dimethyl-2-(alpha-phenyl-o-toloxy)-ethylamine hydrochloride Bristamin hydrochloride (2-(Dimethylamino)ethyl) (o-benzylphenoxy)ether hydrochloride
CAS Number6152-43-8
InChIKeyHMBOWANDONYIBI-UHFFFAOYSA-N
PubChem Substance ID22528
InChIInChI=1S/C17H21NO.ClH/c1-18(2)12-13-19-17-11-7-6-10-16(17)14-15-8-4-3-5-9-15;/h3-11H,12-14H2,1-2H3;1H
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安全信息

RTECSKQ7600000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 305 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 8,219,1958

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 33 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 42,587,1953

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 163 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 42,587,1953

系列性分类

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