Hyoscyamine sulphate 硫酸天仙子胺水合物

CAS 620-61-1 MFCD00078244

化学结构图

620-61-1
SMILES: CN1[C@H]2CC[C@@H]1C[C@H](OC(=O)[C@H](CO)c1ccccc1)C2.CN1[C@H]2CC[C@@H]1C[C@H](OC(=O)[C@H](CO)c1ccccc1)C2.O=S(=O)(O)O

化学属性

Mol. FormulaC34H46N2O6.H2O4S
Mol. Weight676.90
Melting Point205-206 ºC
Refractive index-28 ° (C=5, H2O)

别名和识别编码

Chemical NameHyoscyamine Sulfate Hydrate
EC Number210-644-6
Synonym NuLev levsinsulfate Levsin sulfate Hyoscyamine sulfate (2:1) (salt) 1-alpha-h,5-alpha-h-tropan-3-alpha-ol,(-)-tropate(ester),sulfate(2:1) (-)-HYOSCYAMINE SULFATE Levsinex Hyoscyamine sulfate hydrate L-TROPINE TROPATE SULFATE Benzeneacetic acid, α-(hydroxymethyl)-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, [3(S)-endo]-, sulfate (2:1) (salt) egazil Egazil [3(s)-endo]-lestesulfate(2:1)(salt) Benzeneacetic acid, α-(hydroxymethyl)-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, (αS)-, sulfate (2:1) (salt) L-HYOSCYAMINE SULFATE 硫酸茛菪素 HYOSCYAMINE SULFATE (-)-Hyoscyamine sulfate L-Hyoscyamine Hemisulfate Hyoscyamine sulfuric acid HYOSCYAMINESULFATE(ANHYDROUS) Hyoscyaminsulfat Hyoscyamine sulfate (2:1) Hyoscyamine sulfate L-HYOSCYAMINE SULFATE HEMISULFATE SALT
CAS Number620-61-1
MDL NumberMFCD00078244
Chemical Name Translation硫酸天仙子胺水合物
Merck Number4858
Reaxys-RN11339012
Beilstein Registry Number21(3/4)182
PubChem Substance ID87570852
LabNetwork Molecule IDLN01808635
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

相关文献及参考

  • [2]. Harald John, et al. Application of an enantioselective LC-ESI MS/MS procedure to determine R- and S-hyoscyamine following intravenous atropine administration in swine. Drug Test Anal. Mar-Apr 2012;4(3-4):194-8.
  • [1]. Lars Göran Axelsson, et al. Regulatory role of 5-HT and muscarinic receptor antagonists on the migrating myoelectric complex in rats. Eur J Pharmacol. 2003 Apr 25;467(1-3):211-8.
  • [1]. Lars Göran Axelsson, et al. Regulatory role of 5-HT and muscarinic receptor antagonists on the migrating myoelectric complex in rats. Eur J Pharmacol. 2003 Apr 25;467(1-3):211-8.
  • [2]. Harald John, et al. Application of an enantioselective LC-ESI MS/MS procedure to determine R- and S-hyoscyamine following intravenous atropine administration in swine. Drug Test Anal. Mar-Apr 2012;4(3-4):194-8.

安全信息

Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S1 Keep locked up 上锁；
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
RTECSYM6107000
Risk Statements
  • R26/28 Very toxic by inhalation and if swallowed 吸入及吞食都有剧毒
Hazard Class6.1
GHS Symbol
UN Number 1544
Signal word
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P310+P330
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P302+P350
  • P304+P340+P311
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P361 Remove/Take off immediately all contaminated clothing. 立即去除/脱掉所有被污染的衣服。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
Hazard statements
  • H301+H311+H331
Packing GroupIII 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - infant
DOSE/DURATION           : 400 uL/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Cardiac - pulse rate increase, without fall in BP
   Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
   AJEMEN American Journal of Emergency Medicine.  (WB Saunders, Philadelphia,
   PA)  V.1-    1983-  Volume(issue)/page/year: 15,532,1997

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - infant
DOSE/DURATION           : 400 uL/kg/1D-I
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Cardiac - pulse rate increase, without fall in BP
   Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
   AJEMEN American Journal of Emergency Medicine.  (WB Saunders, Philadelphia,
   PA)  V.1-    1983-  Volume(issue)/page/year: 15,532,1997

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - infant
DOSE/DURATION           : 800 uL/kg/1D-I
TOXIC EFFECTS :
   Behavioral - irritability
   Cardiac - pulse rate increase, without fall in BP
   Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
   AJEMEN American Journal of Emergency Medicine.  (WB Saunders, Philadelphia,
   PA)  V.1-    1983-  Volume(issue)/page/year: 15,532,1997

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 210 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   22

其他信息

  • MOL 文件:620-61-1.mol
  • Sigma Aldrich:620-61-1(sigmaaldrich)
  • 硫酸茛菪素价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 H0453 硫酸天仙子胺水合物 Hyoscyamine Sulfate Hydrate 5G 999元 2014/06/02 H0453 硫酸天仙子胺水合物 Hyoscyamine Sulfate Hydrate 25G 2740元
  • TCI Shanghai:硫酸天仙子胺水合物 Hyoscyamine Sulfate Hydrate,>;98.0%(LC)(T)(620-61-1)

系列性分类

  1. Life Science 生命科学
  2. Biochemistry / Glyco-Chemistry
  3. Alkaloids
  1. Medical Research Areas
  2. GPCR & G Protein
  3. mAChR  (毒蕈碱型乙酰胆碱受体)

相关产品推荐