adiphenine 屈阿生丁

CAS 64-95-9 MFCD N/A

化学结构图

64-95-9
SMILES: CCN(CC)CCOC(=O)C(c1ccccc1)C1CCCCC1

化学属性

Mol. FormulaC20H25NO2
Mol. Weight311.46

别名和识别编码

Chemical NameAcetic acid, diphenyl-, 2-(diethylamino)ethyl ester
Chemical Name Translation屈阿生丁
Chemicalbook IDCB6875570
Wiswesser Line Notation2N2&2OVYR&R
Synonym 2-Diethylaminoethyl diphenylacetate Diphenylacetic acid, 2-(diethylamino)ethyl ester Tranzetil Trasentine Benzeneacetic acid, alpha-phenyl-, 2-(diethylamino)ethyl ester, Difacil Ester dwuetyloaminoetylowy kwasu dwufenylooctowego Vegantine Diphacyl 2-Diethylaminoethylester kyseliny difenyloctove Adiphenin Diphenylacetic acid diethylaminoethyl ester Trazentyna Wegantyna Patrovine SKF 962A Diphenylacetyldiethylaminoethanol Adiphenine Spasmolytin Diphacil Trasentin
CAS Number64-95-9
Beilstein Registry Number1887268
PubChem Substance ID2031
InChIInChI=1S/C20H25NO2/c1-3-21(4-2)15-16-23-20(22)19(17-11-7-5-8-12-17)18-13-9-6-10-14-18/h5-14,19H,3-4,15-16H2,1-2H3
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安全信息

RTECSAH2624000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 30 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CLDND* Compilation of LD50 Values of New Drugs.  (J.R. MacDougal, Dept. of
   National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa,
   Ont., Canada)

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CLDND* Compilation of LD50 Values of New Drugs.  (J.R. MacDougal, Dept. of
   National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa,
   Ont., Canada)

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 35 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 89,131,1947

TYPE OF TEST            : LD50 - L

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 27 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AJDDAL American Journal of Digestive Diseases.  (New York, NY)  V.5-22,
   1938-55; New series: V.1-23, 1956-78.  For publisher information, see
   DDSCDJ.  Volume(issue)/page/year: 18,241,1951

TYPE OF TEST

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系列性分类


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