Nortriptyline

CAS 72-69-5 MFCD00242775

化学结构图

72-69-5
SMILES: CNCCC=C1c2ccccc2CCc2ccccc21

化学属性

Mol. FormulaC19H21N
Mol. Weight263.41

别名和识别编码

Chemical Name5H-Dibenzo(a,d)cycloheptene-delta(sup5),gamma-propylamine, 10,11-dihydro-N-methyl-
Wiswesser Line NotationL C676 BY&T&J BU3M1
Synonym 10,11-Dihydro-N-methyl-5H-dibenzo(a,d)cycloheptene-delta(5,gamma)-propylamine 5-(3-Methylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene Allegron Amitryptyline, demethyl- Apo Nortriptyline Apo-Nortriptyline Avantyl Aventyl Demethylamitriptyline Demethylamitryptyline Desitriptyline Desmethylamitriptylin Desmethylamitriptyline Gen Nortriptyline Gen-Nortriptyline Hydrochloride, Nortriptyline Noramitriptyline Norfenazin Nortrilen Nortriptyline Nortriptyline Hydrochloride Nortryptiline Novo Nortriptyline Novo-Nortriptyline Nu Nortriptyline Nu-Nortriptyline PMS Nortriptyline PMS-Nortriptyline Pamelor Paxtibi ratio
Beilstein Registry Number2216786
CAS Number72-69-5
PubChem Substance ID4543
InChIInChI=1S/C19H21N/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19/h2-5,7-11,20H,6,12-14H2,1H3
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

安全信息

RTECSHO9800000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 370 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 20,1561,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 22 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Behavioral - ataxia
   Behavioral - muscle contraction or spasticity
REFERENCE :
   HEPHD2 Handbook of Experimental Pharmacology.  (Springer-Verlag,
   Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.)  V.50-    1978-
   Volume(issue)/page/year: 55,527,1980

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 17 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 17,65,1974

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 502 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Behavioral - ataxia
   Behavioral - muscle contraction or spasticity
REFERENCE :
   HEPHD2 Handbook of Experimental Pharmacology.  (Springer-Verlag,
   Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.)  V.50-    1978-
   Volume(issue)/page/year: 55,527,1980

TYPE OF TEST

Hazard statements
  • H302 Harmful if swallowed 吞食有害
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P301+P312
  • P301+P317
  • P330 Rinse mouth. 漱口
  • P501 Dispose of contents/container to..… 处理内容物/容器.....

系列性分类

相关产品推荐