Cyclazocine, (+)-

CAS 7313-87-3 MFCD N/A

化学结构图

7313-87-3
SMILES: C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CC1CC1

化学属性

Mol. Weight271.40
Mol. FormulaC18H25NO

别名和识别编码

CAS Number7313-87-3
Chemical Name(+)-Cyclazocine
Synonym (2S,6S,11S)-3-(Cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol (+)-Cyclazocine (+)-cis-Cyclazocine (+)-?-Cyclazocine MCV 4511 NIH 10449 d-Cyclazocine
Chemical Name Translation
PubChem Substance ID6603759
InChIInChI=1S/C18H25NO/c1-12-17-9-14-5-6-15(20)10-16(14)18(12,2)7-8-19(17)11-13-3-4-13/h5-6,10,12-13,17,20H,3-4,7-9,11H2,1-2H3/t12-,17+,18+/m1/s1
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分类

  • Chiral Reagents
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Cyclazocine is a mu opioid antagonist and kappa opioid agonist; it blocks the dopamine response to nicotine

相关文献及参考

  • Remmers, A., et al.: J. Pharmacol. Exper. Ther., 288, 827 (1999),
  • Wentland, M., et al.: Bioorg. Med. Chem. Lett., 11, 623 (2001),

系列性分类

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