Tetrodotoxin, O(sup 4)-methyl-

CAS 7724-39-2 MFCD07724392

化学结构图

7724-39-2
SMILES: CO[C@H]1NC(=N)N[C@]23[C@@H](O)[C@@H]4O[C@](O)(O[C@H]([C@H]4O)[C@H]12)[C@@]3(O)CO

化学属性

Mol. Weight333.34
Mol. FormulaC12H19N3O8

别名和识别编码

Chemical NameTetrodotoxin, O(sup 4)-methyl-
Chemicalbook IDCB32357264
Synonym Methoxytetrodotoxin 4-Methoxytetrodotoxin
Beilstein Registry Number4157437
CAS Number7724-39-2
InChIKeySVOKHTHBCRETOQ-CNKCMGRGSA-N
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安全信息

RTECSXF8887000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 12700 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JJPAAZ Japanese Journal of Pharmacology.  (Japanese Pharmacological Soc.,
   c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto
   606, Japan)  V.1-    1951-  Volume(issue)/page/year: 17,267,1967

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 322 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJPHAZ European Journal of Pharmacology.  (Elsevier Science Pub. B.V., POB
   211, 1000 AE Amsterdam, Netherlands)  V.1-    1967- Volume(issue)/page/year:
   3,58,1968

系列性分类


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