TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Primate - monkey DOSE/DURATION : 326 mg/kg TOXIC EFFECTS : Behavioral - muscle contraction or spasticity Cardiac - arrhythmias (including changes in conduction) Lungs, Thorax, or Respiration - dyspnea REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 58,118,1981