4-(3-Oxobutyl)-1,2-Diphenylpyrazolidine-3,5-Dione 4-(3-氧代丁基)-1,2-二苯基吡唑烷-3,5-二酮

CAS 853-34-9 MFCD00210323

化学结构图

853-34-9
SMILES: CC(=O)CCC1C(=O)N(c2ccccc2)N(c2ccccc2)C1=O

化学属性

Mol. FormulaC19H18N2O3
Mol. Weight322.39

别名和识别编码

Chemical Name4-(3-Oxobutyl)-1,2-Diphenylpyrazolidine-3,5-Dione
CAS Number853-34-9
Synonym Recheton Copirene Keobutane-jade Ketason Chetil Kebuzone Chetazolidin KPB Ketazone Hichillos 4-(3-Oxobutyl)-1,2-diphenyl-3,5-pyrazolidinedione 1,2-Diphenyl-4-(3'-oxobutyl)-3,5-dioxopyrazolidine ######## Pecnon Chebutan gamma-Ketophenylbutazone 1,2-Diphenyl-4-(gamma-ketobutyl)-3,5-pyrazolidinedione Chepirol Ketophenylbutazone
Chemical Name Translation4-(3-氧代丁基)-1,2-二苯基吡唑烷-3,5-二酮
Wiswesser Line NotationT5VNNV EHJ BR& CR& E2V1
Beilstein Registry Number0308507
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分类

  • Aromatics
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Antirheumatic.

相关文献及参考

  • Nemecek., et al.: Arzneim.-Forsch., 16, 1339 (1966),

安全信息

RTECSUQ8540000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURAT

{hazard_com

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 620 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 3,390,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 750 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 8,229,1958

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 683 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 3,390,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 650 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year

系列性分类

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